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By NASA
Improving space-based pharmaceutical research
View of the Ice Cubes experiment #6 (Kirara) floating in the Columbus European Laboratory module aboard the International Space Station.UAE (United Arab Emirates)/Sultan Alneyadi Researchers found differences in the stability and degradation of the anti-Covid drug Remdesivir in space and on Earth on its first research flight, but not on a second. This highlights the need for more standardized procedures for pharmaceutical research in space.
Long-term stability of drugs is critical for future space missions. Because multiple characteristics of spaceflight could influence chemical stability, the scientists repeated their experiment under circumstances as nearly identical as possible. This research used Kirara, a temperature-controlled incubator developed by JAXA (Japan Aerospace Exploration Agency) for crystallizing proteins in microgravity. Results also confirmed that a solubility enhancer used in the drug is radiation resistant and its quality was not affected by microgravity and launch conditions.
Evaluating postflight task performance
A test subject performing a sensorimotor field test on the ground.NASA/Lauren Harnett Immediately after returning from the International Space Station and for up to one week, astronauts perform functional tasks in ways similar to patients on Earth who have a loss of inner ear function. This finding suggests that comparing data from these patients and astronauts could provide insight into the role of the balance and sensory systems in task performance during critical parts of a mission such as landing on the Moon or Mars.
Spaceflight causes changes to the balance (vestibular) and sensory systems that can lead to symptoms such as disorientation and impaired locomotion. Standard Measures collects a set of data, including tests of sensorimotor function, related to human spaceflight risks from astronauts before, during, and after missions to help characterize how people adapt to living and working in space.
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By NASA
4 min read
Preparations for Next Moonwalk Simulations Underway (and Underwater)
The Project F.I.R.E. team, part of Falcon Research Labs and current students at Cerritos Community College in California, is researching the use of drones to extinguish fires as part of a NASA research award called the University Student Research Challenge. From left, Logan Stahl, Juan Villa, Angel Ortega, Larisa Mayoral, Jenny Escobar, and Paola Mayoral-Jimenez.Falcon Research Labs Great ideas, and the talent and passion that bring them to life, can be found anywhere.
In that spirit, NASA’s University Student Research Challenge (USRC) in 2024 selected its first group of community college students to contribute original research to the agency’s transformative vision for 21st century aviation.
The student-led group, from Cerritos Community College in California, is researching a new method of safely extinguishing wildfires using eco-friendly pellets dropped from uncrewed drones they call Project F.I.R.E. (Fire Intervention Retardant Expeller).
“Wildfires are a major problem we’re facing today,” said Angel Ortega, project technical director and lead research engineer for Project F.I.R.E. at Cerritos Community College. “The goal of our research is to demonstrate that our prototype drone with biodegradable fire retardant can successfully put out a controlled fire.”
A Community College First
Until now, USRC has only selected participants from traditional four-year institutions, compared to a two-year community college. This award exemplifies the activity’s goal of giving all of tomorrow’s aeronautical innovators a shot at NASA support for their research ideas.
“The University Innovation (UI) project provides a number of different avenues for students to contribute to aeronautics,” said Steven Holz, who manages the USRC award process. “All of the opportunities are different and help build knowledge and skills that would be advantageous to those wanting to continue working on UI opportunities or within NASA.”
This award is one of two from NASA’s USRC selected in 2024. The team received the USRC award prior to the devastating Los Angeles fires of January 2025.
“Our thoughts are with everyone affected by this tragedy,” members of the team said in a statement. “As a team, we are deeply committed to advancing innovative solutions to enhance safety and resilience, working toward a future where communities are better protected against such disasters.”
Innovating a Solution
The six team members of Project F.I.R.E. are driven by an ethic of public service. As fires continue to affect communities in their native southern California, they are applying their skills to finding a way to help.
“We want to get the public inspired that there are possible solutions at hand,” Ortega said. “And the work we’re doing now can hopefully build towards that bigger goal of a widespread solution.”
The research they are pursuing involves dropping biodegradable pellets into fires from uncrewed, autonomous drones. The pellets, upon reaching the ground, combine chemical ingredients which create a foamlike solution of fire retardant that will not contaminate the environment after the fire is extinguished.
Project F.I.R.E.’s innovative idea for fire suppression involves releasing eco-friendly foam pellets from uncrewed drones.Falcon Research Labs The team is keen to support firefighters and wildland fire managers and keep them safe while managing these natural disasters. The group has met with firefighters, discussed the idea with them, and received useful feedback on how to make the technology work best in the field.
Though the group is only at the outset of the research, their idea has existed for longer.
Blue Skies Forever
Prior to applying for a USRC, Project F.I.R.E. also presented at NASA’s 2024 Gateway to Blue Skies competition, in which they won the “Future Game-Changer” award.
Through Gateway to Blue Skies, NASA challenges college students to research climate-friendly technologies and applications related to the future of aviation and present them at an annual forum.
Following Project F.I.R.E.’s participation in the forum, they applied for a USRC grant to begin turning their vision into reality.
“Our experience with NASA has been incredibly supportive and inspiring,” said Logan Stahl, the project’s operations director. “We thought competing against some of the other schools would be intimidating, but the experience we’ve had is the complete opposite. Everyone was very welcoming, and the NASA representatives communicated with us and asked questions.”
The USRC support will allow the team to build on their earlier foundations, they said.
“Because Gateway to Blue Skies is more conceptual, it let us bring our idea to the table. Now through USRC, we can start building hands-on and make our idea come to life,” said Larisa Mayoral, chemical engineer and laboratory operations manager.
The Project F.I.R.E. team receives their “Future Game-Changer” award during the 2024 Gateway to Blue Skies forum held at NASA’s Ames Research Center in California.NASA / Brandon Torres The team expressed gratitude, speaking as community college students, for their ability to participate in and contribute research at a level that competes with top-brass universities.
“We’re very appreciative of our college and NASA providing us this opportunity,” said Paola Mayoral Jimenez, laboratory coordinator and safety manager. “By doing this project, we hope to shine a light on community colleges, their students, and what they have to offer.”
Complete details on USRC awardees and solicitations, such as what to include in a proposal and how to submit it, are available on the NASA Aeronautics Research Mission Directorate solicitation page.
About the Author
John Gould
Aeronautics Research Mission DirectorateJohn Gould is a member of NASA Aeronautics' Strategic Communications team at NASA Headquarters in Washington, DC. He is dedicated to public service and NASA’s leading role in scientific exploration. Prior to working for NASA Aeronautics, he was a spaceflight historian and writer, having a lifelong passion for space and aviation.
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Last Updated Feb 23, 2025 EditorJim BankeContactAngela Surgenorangela.d.surgenor@nasa.gov Related Terms
Aeronautics Aeronautics Research Mission Directorate Flight Innovation Transformative Aeronautics Concepts Program University Innovation University Student Research Challenge View the full article
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By Space Force
The DARC partnership is completing construction at the first of three sites that will host a global network of advanced ground-based sensors.
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