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By NASA
4 min read
Preparations for Next Moonwalk Simulations Underway (and Underwater)
The mystery of why life uses molecules with specific orientations has deepened with a NASA-funded discovery that RNA — a key molecule thought to have potentially held the instructions for life before DNA emerged — can favor making the building blocks of proteins in either the left-hand or the right-hand orientation. Resolving this mystery could provide clues to the origin of life. The findings appear in research recently published in Nature Communications.
Proteins are the workhorse molecules of life, used in everything from structures like hair to enzymes (catalysts that speed up or regulate chemical reactions). Just as the 26 letters of the alphabet are arranged in limitless combinations to make words, life uses 20 different amino acid building blocks in a huge variety of arrangements to make millions of different proteins. Some amino acid molecules can be built in two ways, such that mirror-image versions exist, like your hands, and life uses the left-handed variety of these amino acids. Although life based on right-handed amino acids would presumably work fine, the two mirror images are rarely mixed in biology, a characteristic of life called homochirality. It is a mystery to scientists why life chose the left-handed variety over the right-handed one.
A diagram of left-handed and right-handed versions of the amino acid isovaline, found in the Murchison meteorite.NASA DNA (deoxyribonucleic acid) is the molecule that holds the instructions for building and running a living organism. However, DNA is complex and specialized; it “subcontracts” the work of reading the instructions to RNA (ribonucleic acid) molecules and building proteins to ribosome molecules. DNA’s specialization and complexity lead scientists to think that something simpler should have preceded it billions of years ago during the early evolution of life. A leading candidate for this is RNA, which can both store genetic information and build proteins. The hypothesis that RNA may have preceded DNA is called the “RNA world” hypothesis.
If the RNA world proposition is correct, then perhaps something about RNA caused it to favor building left-handed proteins over right-handed ones. However, the new work did not support this idea, deepening the mystery of why life went with left-handed proteins.
The experiment tested RNA molecules that act like enzymes to build proteins, called ribozymes. “The experiment demonstrated that ribozymes can favor either left- or right-handed amino acids, indicating that RNA worlds, in general, would not necessarily have a strong bias for the form of amino acids we observe in biology now,” said Irene Chen, of the University of California, Los Angeles (UCLA) Samueli School of Engineering, corresponding author of the Nature Communications paper.
In the experiment, the researchers simulated what could have been early-Earth conditions of the RNA world. They incubated a solution containing ribozymes and amino acid precursors to see the relative percentages of the right-handed and left-handed amino acid, phenylalanine, that it would help produce. They tested 15 different ribozyme combinations and found that ribozymes can favor either left-handed or right-handed amino acids. This suggested that RNA did not initially have a predisposed chemical bias for one form of amino acids. This lack of preference challenges the notion that early life was predisposed to select left-handed-amino acids, which dominate in modern proteins.
“The findings suggest that life’s eventual homochirality might not be a result of chemical determinism but could have emerged through later evolutionary pressures,” said co-author Alberto Vázquez-Salazar, a UCLA postdoctoral scholar and member of Chen’s research group.
Earth’s prebiotic history lies beyond the oldest part of the fossil record, which has been erased by plate tectonics, the slow churning of Earth’s crust. During that time, the planet was likely bombarded by asteroids, which may have delivered some of life’s building blocks, such as amino acids. In parallel to chemical experiments, other origin-of-life researchers have been looking at molecular evidence from meteorites and asteroids.
“Understanding the chemical properties of life helps us know what to look for in our search for life across the solar system,” said co-author Jason Dworkin, senior scientist for astrobiology at NASA’s Goddard Space Flight Center in Greenbelt, Maryland, and director of Goddard’s Astrobiology Analytical Laboratory.
Dworkin is the project scientist on NASA’s OSIRIS-REx mission, which extracted samples from the asteroid Bennu and delivered them to Earth last year for further study.
“We are analyzing OSIRIS-REx samples for the chirality (handedness) of individual amino acids, and in the future, samples from Mars will also be tested in laboratories for evidence of life including ribozymes and proteins,” said Dworkin.
The research was supported by grants from NASA, the Simons Foundation Collaboration on the Origin of Life, and the National Science Foundation. Vázquez-Salazar acknowledges support through the NASA Postdoctoral Program, which is administered by Oak Ridge Associated Universities under contract with NASA.
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Last Updated Nov 21, 2024 EditorWilliam SteigerwaldContactNancy N. Jonesnancy.n.jones@nasa.govLocationGoddard Space Flight Center Related Terms
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By NASA
5 min read
Preparations for Next Moonwalk Simulations Underway (and Underwater)
NASA provides a variety of pathways for those outside the agency to contribute to authentic and meaningful research. Whether you’re a student pursuing a degree in STEM (science, technology, engineering, or mathematics), an educator looking for new ways to engage your classroom, or a citizen scientist enthusiastic about sharing your observations, there’s a wide array of opportunities to get involved in NASA research.
Citizen scientists around the world participate in environmental observation and measurement efforts through GLOBE.NASA Everybody
People from all around the world can make contributions to NASA research through citizen science projects and other opportunities available to the public.
Share your observations and take measurements in your part of the world through GLOBE (Global Learning and Observations to Benefit the Environment), an international science and education initiative that engages students, teachers, and the public in collecting and analyzing environmental data. Do you have a relevant idea for human health science research that could be performed on the future Gateway lunar space station? Follow these steps to share your idea for consideration. The Prizes, Challenges, and Crowdsourcing program through NASA’s Space Technology Mission Directorate invites citizen scientists to develop innovations in recycling material waste on deep space missions, develop aids/devices for navigating on the lunar surface during future Artemis missions, and more. Do you have the “right stuff” to participate in a simulated deep space mission? NASA’s HERA (the Human Exploration Research Analog) is seeking healthy subjects to participate in 45-day simulations to study the physiological and psychological effects of isolation and confinement on humans to help prepare for future missions to the Moon and Mars. Visit the NASA Citizen Science webpage for more opportunities to discover the secrets of the universe, search for life elsewhere, and improve life on Earth and in space. This collage features the winning designs in the 2024 Dream with Us Design Challenge, which asks students to dream of innovations for the future of aviation.NASA Middle and High School Students
Students can gain valuable experience while making a difference in the future of aeronautics and exploration.
Rising high school juniors and seniors are eligible to apply for the four-week Gene Lab for High School Students training program sponsored by NASA’s Ames Research Center in Silicon Valley, California. The program focuses on collecting and analyzing complex biological data such as genetic codes, and computational biology. Through the annual TechRise Student Challenge offered by NASA’s Space Technology Mission Directorate, U.S. students in grades 6 to 12 form teams and design an experiment to fly on a suborbital flight platform such as a high-altitude balloon. Interested in aviation? The Dream With Us Design Challenge through NASA’s Aeronautics Research Mission Directorate invites students in grades 6 to 12 to envision new innovations that will improve the safety, sustainability, and accessibility of aviation systems and technology. Through NASA internships, U.S. students ages 16 and up can boost their research experience and contribute to NASA’s work with the guidance of an agency mentor. This collage features the winning designs in the 2024 Dream with Us Design Challenge, which asks students to dream of innovations for the future of aviation.NASA Undergraduate and Graduate Students
NASA offers a variety of research opportunities for college students preparing to launch their own exciting careers in STEM.
NASA’s Established Program to Stimulate Competitive Research (EPSCoR) grants competitive awards to enable college and university students within specific U.S. jurisdictions to participate in cutting-edge research projects that address NASA’s challenges and needs. The National Space Grant College and Fellowship Project (Space Grant), is a national network of colleges and universities comprising a total of 52 consortia across the U.S. These consortia fund several research opportunities for students attending member colleges and universities. Look up your state’s Space Grant consortium website to discover available opportunities. NASA internships are available in a wide range of opportunities for undergraduate and graduate students, enabling meaningful contributions to NASA’s missions as well as authentic experience as a part of the agency’s world-class workforce. Through the University Student Research Challenge, students are invited to propose their ideas describing innovative new approaches to tackling one of six major research areas as outlined by NASA’s Aeronautics Research Mission Directorate. Students can take part in valuable studies of the ever-changing Earth system through NASA’s Earth Science Division’s Early Career Research (ECR) program. ECR includes the eight-week Student Airborne Research Program, the Climate Change Research Initiative, and more. College students at Minority Serving Institutions can contribute to the agency’s exploration goals through many opportunities offered by NASA’s Minority University Research and Education Project (MUREP). Educators of grades K-8 take part in a workshop hosted by NASA’s Next Gen STEM.NASA Educators
NASA provides opportunities for educators to participate in authentic aerospace research, as well as to engage their students in research in the classroom.
Space Grant offers a variety of opportunities for educators, from curriculum enhancement and faculty development to grants enabling teachers to bring NASA research into the classroom. Look up your state’s Space Grant consortium website to discover available opportunities. NASA welcomes interns with professional teaching experience to help foster the education and curiosity of students who will shape the future workforce. Visit NASA Internships to learn more and find current opportunities. Through NASA’s Climate Change Research Initiative, part of the agency’s Earth Science Division’s Early Career Research Program, high school STEM educators can join a research team led by NASA scientists to focus on a research area related to climate change. There’s More to Explore
Explore available NASA STEM learning experiences, such as internship roles, student competitions, or engagements with NASA researchers, through NASA’s STEM Gateway platform. Visit NASA’s Learning Resources webpage for the latest news and resources from the agency’s Office of STEM Engagement.
Keep Exploring Discover More STEM Topics From NASA
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By NASA
Hubble Space Telescope Home NASA’s Hubble, MAVEN… Missions Hubble Home Overview About Hubble The History of Hubble Hubble Timeline Why Have a Telescope in Space? Hubble by the Numbers At the Museum FAQs Impact & Benefits Hubble’s Impact & Benefits Science Impacts Cultural Impact Technology Benefits Impact on Human Spaceflight Astro Community Impacts Science Hubble Science Science Themes Science Highlights Science Behind Discoveries Hubble’s Partners in Science Universe Uncovered Explore the Night Sky Observatory Hubble Observatory Hubble Design Mission Operations Missions to Hubble Hubble vs Webb Team Hubble Team Career Aspirations Hubble Astronauts News Hubble News Hubble News Archive Social Media Media Resources Multimedia Multimedia Images Videos Sonifications Podcasts E-books Lithographs Fact Sheets Glossary Posters Hubble on the NASA App More Online Activities 6 min read
NASA’s Hubble, MAVEN Help Solve the Mystery of Mars’ Escaping Water
NASA, ESA, STScI, John T. Clarke (Boston University); Processing: Joseph DePasquale (STScI) Mars was once a very wet planet as is evident in its surface geological features. Scientists know that over the last 3 billion years, at least some water went deep underground, but what happened to the rest? Now, NASA’s Hubble Space Telescope and MAVEN (Mars Atmosphere and Volatile Evolution) missions are helping unlock that mystery.
“There are only two places water can go. It can freeze into the ground, or the water molecule can break into atoms, and the atoms can escape from the top of the atmosphere into space,” explained study leader John Clarke of the Center for Space Physics at Boston University in Massachusetts. “To understand how much water there was and what happened to it, we need to understand how the atoms escape into space.”
Clarke and his team combined data from Hubble and MAVEN to measure the number and current escape rate of the hydrogen atoms escaping into space. This information allowed them to extrapolate the escape rate backwards through time to understand the history of water on the Red Planet.
Escaping Hydrogen and “Heavy Hydrogen”
Water molecules in the Martian atmosphere are broken apart by sunlight into hydrogen and oxygen atoms. Specifically, the team measured hydrogen and deuterium, which is a hydrogen atom with a neutron in its nucleus. This neutron gives deuterium twice the mass of hydrogen. Because its mass is higher, deuterium escapes into space much more slowly than regular hydrogen.
Over time, as more hydrogen was lost than deuterium, the ratio of deuterium to hydrogen built up in the atmosphere. Measuring the ratio today gives scientists a clue to how much water was present during the warm, wet period on Mars. By studying how these atoms currently escape, they can understand the processes that determined the escape rates over the last four billion years and thereby extrapolate back in time.
Although most of the study’s data comes from the MAVEN spacecraft, MAVEN is not sensitive enough to see the deuterium emission at all times of the Martian year. Unlike the Earth, Mars swings far from the Sun in its elliptical orbit during the long Martian winter, and the deuterium emissions become faint. Clarke and his team needed the Hubble data to “fill in the blanks” and complete an annual cycle for three Martian years (each of which is 687 Earth days). Hubble also provided additional data going back to 1991 – prior to MAVEN’s arrival at Mars in 2014.
The combination of data between these missions provided the first holistic view of hydrogen atoms escaping Mars into space.
These are far-ultraviolet Hubble images of Mars near its farthest point from the Sun, called aphelion, on December 31, 2017 (top), and near its closest approach to the Sun, called perihelion, on December 19, 2016 (bottom). The atmosphere is clearly brighter and more extended when Mars is close to the Sun.
Reflected sunlight from Mars at these wavelengths shows scattering by atmospheric molecules and haze, while the polar ice caps and some surface features are also visible. Hubble and MAVEN showed that Martian atmospheric conditions change very quickly. When Mars is close to the Sun, water molecules rise very rapidly through the atmosphere, breaking apart and releasing atoms at high altitudes. NASA, ESA, STScI, John T. Clarke (Boston University); Processing: Joseph DePasquale (STScI)
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A Dynamic and Turbulent Martian Atmosphere
“In recent years scientists have found that Mars has an annual cycle that is much more dynamic than people expected 10 or 15 years ago,” explained Clarke. “The whole atmosphere is very turbulent, heating up and cooling down on short timescales, even down to hours. The atmosphere expands and contracts as the brightness of the Sun at Mars varies by 40 percent over the course of a Martian year.”
The team discovered that the escape rates of hydrogen and deuterium change rapidly when Mars is close to the Sun. In the classical picture that scientists previously had, these atoms were thought to slowly diffuse upward through the atmosphere to a height where they could escape.
But that picture no longer accurately reflects the whole story, because now scientists know that atmospheric conditions change very quickly. When Mars is close to the Sun, the water molecules, which are the source of the hydrogen and deuterium, rise through the atmosphere very rapidly releasing atoms at high altitudes.
The second finding is that the changes in hydrogen and deuterium are so rapid that the atomic escape needs added energy to explain them. At the temperature of the upper atmosphere only a small fraction of the atoms have enough speed to escape the gravity of Mars. Faster (super-thermal) atoms are produced when something gives the atom a kick of extra energy. These events include collisions from solar wind protons entering the atmosphere or sunlight that drives chemical reactions in the upper atmosphere.
Mars was once a very wet planet. Scientists know that over the last 3 billion years, some of the water went underground, but what happened to the rest? Credit: NASA’s Goddard Space Flight Center; Lead Producer: Paul Morris; Mars Animations Producer: Dan Gallagher Serving as a Proxy
Studying the history of water on Mars is fundamental not only to understanding planets in our own solar system but also the evolution of Earth-size planets around other stars. Astronomers are finding more and more of these planets, but they’re difficult to study in detail. Mars, Earth and Venus all sit in or near our solar system’s habitable zone, the region around a star where liquid water could pool on a rocky planet; yet all three planets have dramatically different present-day conditions. Along with its sister planets, Mars can help scientists grasp the nature of far-flung worlds across our galaxy.
These results appear in the July 26 edition of Science Advances, published by the American Association for the Advancement of Science.
About the Missions
The Hubble Space Telescope has been operating for over three decades and continues to make ground-breaking discoveries that shape our fundamental understanding of the universe. Hubble is a project of international cooperation between NASA and ESA (European Space Agency). NASA’s Goddard Space Flight Center in Greenbelt, Maryland, manages the telescope and mission operations. Lockheed Martin Space, based in Denver, Colorado, also supports mission operations at Goddard. The Space Telescope Science Institute (STScI) in Baltimore, Maryland, which is operated by the Association of Universities for Research in Astronomy, conducts Hubble science operations for NASA.
MAVEN’s principal investigator is based at the Laboratory for Atmospheric and Space Physics (LASP) at the University of Colorado Boulder. LASP is also responsible for managing science operations and public outreach and communications. NASA’s Goddard Space Flight Center in Greenbelt, Maryland, manages the MAVEN mission. Lockheed Martin Space built the spacecraft and is responsible for MAVEN mission operations at Goddard. NASA’s Jet Propulsion Laboratory in Southern California provides navigation and Deep Space Network support. The MAVEN team is preparing to celebrate the spacecraft’s 10th year at Mars in September 2024.
Facebook logo @NASAHubble @NASAHubble Instagram logo @NASAHubble Media Contacts:
Claire Andreoli
NASA’s Goddard Space Flight Center, Greenbelt, MD
claire.andreoli@nasa.gov
Ann Jenkins and Ray Villard
Space Telescope Science Institute, Baltimore, MD
Science Contact:
John T. Clarke
Boston University, Boston, MA
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Last Updated Sep 05, 2024 Editor Andrea Gianopoulos Location NASA Goddard Space Flight Center Related Terms
Astrophysics Astrophysics Division Goddard Space Flight Center Hubble Space Telescope Mars MAVEN (Mars Atmosphere and Volatile EvolutioN) Missions Planetary Science Planets Science Mission Directorate The Solar System Keep Exploring Discover More Topics From Hubble and Maven
Hubble Space Telescope
Since its 1990 launch, the Hubble Space Telescope has changed our fundamental understanding of the universe.
Hubble Science Highlights
MAVEN
The Mars Atmosphere and Volatile EvolutioN (MAVEN) mission is the first mission devoted to understanding the Martian upper atmosphere.
Mars
Mars is the fourth planet from the Sun, and the seventh largest. It’s the only planet we know of inhabited…
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