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By NASA
Parallels between spaceflight and the aging process may extend to encompass frailty.
Figure Left: Venn diagram of differentially expressed frailty genes in rodent and human samples shows the common differentially expressed genes between the two species.
Figure Right: Schematic of the Inspiration4 experiments and samples.
This study relied on data from the OSDR, including 7 rodent spaceflight datasets, 2 human space analog datasets, astronaut data from the Japan Aerospace Exploration Agency (JAXA) and Inspiration4. Data on sarcopenia were mined from National Center for Biotechnology Information’s Gene Expression Omnibus. Spaceflight accelerates the symptoms of aging in astronaut bodies by inducing genomic instability, mitochondrial dysfunction, and increased inflammation. This is the first study to comprehensively examine biomarkers and pathways associated with spaceflight and terrestrial aging, frailty, and sarcopenia.
Main Findings:
Spaceflight induced notable changes in gene expression patterns related to frailty and muscle loss indicative of a frailty-like condition. Exposure to the space environment leads to changes related to inflammation, muscle wasting, and other age-related features observed in both mice and humans. Parallels between spaceflight and the aging process may extend to also encompass frailty. Impact: This work reveals the need for a frailty index to monitor development of frailty-related astronaut health risks during spaceflight. The results provide insights into potential avenues for developing countermeasures to combat frailty-related health risks for both astronauts and aging populations on Earth.
This study was part of the 44-article Space Omics and Medical Atlas (SOMA) package published in Nature. It demonstrates the effectiveness of open science combined with robust data submission, standards, and curation. The study began within and was organized through the Analysis Working Groups (AWGs) of NASA’s Open Science Data Repository (OSDR).
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By NASA
Johnson Space Center Vibration Test FacilityNASA Nov. 14, 2024
NASA Johnson Invites Proposals to Lease Vibration Test Facility
NASA’s Johnson Space Center is seeking proposals for the use of its historic, but underused, Vibration and Acoustic Test Facility. Prospective tenants must submit facility walk-through requests by Monday, Nov. 18.
Final proposals are due by 12 p.m. EST Monday, Dec. 16, and must promote activities that will build, expand, modernize, or operate aerospace-related capabilities at NASA Johnson and help preserve the historic and iconic building through preservation and adaptive reuse.
NASA plans to sign a National Historic Preservation Act (NHPA) lease agreement for the facility, also known as Building 49, for a five-year base period and one five-year extension to be negotiated between NASA and the tenant. To request a walk-through, send an email to hq-realestate@mail.nasa.gov.
“This historic facility has been used for decades to ensure the success and safety of all human spaceflight missions by putting engineering designs and hardware to the ultimate stress tests,” said NASA Johnson Director Vanessa Wyche. “For more than 60 years, NASA Johnson has been the hub of human space exploration and this agreement will be a vital part of the center’s efforts to develop a robust and durable space economy that refines our understanding of the solar system and space exploration.”
All proposals must adhere to the guidelines detailed in the Agency Announcement for Proposals describing concept plans for development of the property, including any modifications proposed to the building; a statement of financial capability to successfully achieve and sustain operations, demonstrated experience with aerospace-related services or other space-related activities, and a detailed approach to propelling the space economy.
The nine-story building complex has a gross square footage of 62,737 square feet and consists of a north wing measuring 62 feet long, 268 feet wide and 106 feet tall, and a central wing about 64 feet long and 115 feet wide. Building 49 currently houses five laboratories, including the General Vibration Laboratory, Modal Operations Laboratory, Sonic Fatigue Laboratory, Spacecraft Acoustic Laboratory, and Spacecraft Vibration Laboratory. The south administrative portion of the building is not included in the property offered for lease.
As the home of Mission Control Center for the agency’s human space missions, astronaut training, robotics, human health and space medicine, NASA Johnson leads the way for the human exploration. Leveraging its unique role and location, the center is developing multiple lease agreements, including the recently announced Exploration Park, to sustain its key role in helping the human spaceflight community foster a robust space.
In the coming years, NASA and its academic, commercial, and international partners will see the completion of the International Space Station Program, the commercial development of low Earth orbit, and the first human Artemis campaign missions establishing sustainable human presence on the Moon in preparation for human missions to Mars.
Johnson already is leading the commercialization of space with the commercial cargo and crew programs and private astronaut missions to the space station. The center also is supporting the development of commercial space stations in low Earth orbit, and lunar-capable commercial spacesuits and lunar landers that will be provided as services to both NASA and the private sector to accelerate human access to space. Through the development of Exploration Park, the center will broaden the scope of the human spaceflight community that is tackling the many difficult challenges ahead.
Learn more about NASA Johnson’s efforts to collaborate with industry partners:
https://www.nasa.gov/johnson/frontdoor
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Kelly Humphries
Johnson Space Center, Houston
281-483-5111
kelly.o.humphries@nasa.gov
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By NASA
Peru’s Vice Minister of Defense Policies for Ministry of Defense César Medardo Torres Vega, NASA Administrator Bill Nelson, and Director of Peru’s National Commission for Aerospace Research and Development (CONIDA) Maj. Gen. Roberto Melgar Sheen meet in Lima, Peru, Nov. 14, 2024, where the U.S. and Peru signed a memorandum of understanding agreeing to study a potential sounding rocket campaign.Credit: U.S. Embassy Peru NASA and Peru’s National Commission for Aerospace Research and Development (CONIDA) laid the groundwork for a potential multi-year scientific rocket launch campaign in the South American country.
Both countries signed a non-binding memorandum of understanding Thursday that includes safety training, a joint feasibility study for the potential campaign, and technical assistance for CONIDA on sounding rocket launches. Sounding rockets are small, low-cost rockets that provide suborbital access to space.
“We are excited to look at the possibility of once again launching sounding rockets from Peru,” said NASA Administrator Bill Nelson, who signed on behalf of the United States. “This agreement deepens our international partnership with Peru and the scientific research we conduct because of the country’s location along the magnetic equator. Together we will go farther.”
Maj. Gen. Roberto Melgar Sheen, head of CONIDA, signed on behalf of Peru. Brian Nichols, assistant secretary for Western Hemisphere Affairs for the U.S. State Department, and Stephanie Syptak-Ramnath, U.S. ambassador to Peru, also participated, among other Peruvian officials. The event took place during the week of the Asia-Pacific Economic Cooperation forum beginning Nov. 9 in Lima.
During his visit to Peru, Nelson also discussed the importance of international partnerships and collaboration in space and celebrated Peru’s signing of the Artemis Accords earlier this year.
The United States and Peru have a long history of space cooperation. NASA conducted sounding rocket campaigns at CONIDA’s Punta Lobos launch base in 1975 and 1983.
NASA uses sounding rockets to carry scientific instruments into space on suborbital flights to collect important science data and test prototype instruments. They yield invaluable data that enhance our understanding of Earth’s atmosphere and weather, our solar system, and the universe, and test equipment for deeper space travel.
Understanding our Earth’s atmosphere and how it is influenced by the Sun is crucial to protecting ground and space-based assets that we rely on every day, from the power grid to weather data and even navigation.
For more information about NASA’s international partnerships, visit:
https://www.nasa.gov/oiir
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Meira Bernstein / Elizabeth Shaw
Headquarters, Washington
202-358-1600
meira.b.bernstein@nasa.gov / elizabeth.a.shaw@nasa.gov
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Last Updated Nov 14, 2024 EditorJessica TaveauLocationNASA Headquarters Related Terms
Office of International and Interagency Relations (OIIR) Sounding Rockets View the full article
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By NASA
4 min read
Preparations for Next Moonwalk Simulations Underway (and Underwater)
The laser that transmits between NASA’s Psyche spacecraft and Earth-based observatories for the Deep Space Optical Communications experiment successfully reaches its target thanks, in part, to a vibration isolation platform developed by Controlled Dynamics Inc., and supported by several Space Technology Mission Directorate programs. NASA/JPL-Caltech One year ago today, the future of space communications arrived at Earth as a beam of light from a NASA spacecraft nearly 10 million miles away. That’s 40 times farther than our Moon. That’s like using a laser pointer to track a moving dime from a mile away. That’s pretty precise.
That laser — transmitted from NASA’s DSOC (Deep Space Optical Communications) technology demonstration — has continued to hit its target on Earth from record-breaking distances.
“NASA’s Deep Space Optical Communications features many novel technologies that are needed to precisely point and track the uplink beacon and direct the downlink laser,” said Bill Klipstein, DSOC project manager at NASA’s Jet Propulsion Laboratory in Southern California.
One of the technologies aiding that extremely precise pointing was invented by a small business and fostered by NASA for more than a decade.
Whole Lotta Shakin’ Going On (Not!)
Part of the challenge with the precision pointing needed for DSOC was isolating the laser from the spacecraft’s vibrations, which would nudge the beam off target. Fortunately for NASA, Controlled Dynamics Inc. (CDI), in Huntington Beach, California, offered a solution to this problem.
The company had a platform designed to isolate orbiting experiments from vibrations caused by their host spacecraft, other payloads, crew movements, or even their own equipment. Just as the shocks on a car provide a smoother ride, the struts and actuators on CDI’s vibration isolation platform created a stable setting for delicate equipment.
This idea needed to be developed and tested first to prove successful.
The Path to Deep Space Success
NASA’s Space Technology Mission Directorate started supporting the platform’s development in 2012 under its Game Changing Development program with follow-on support from the SBIR (Small Business Innovation Research) program. The technology really began to take off — pun intended — under NASA’s Flight Opportunities program. Managed out of NASA’s Armstrong Flight Research Center in Edwards, California, Flight Opportunities rapidly demonstrates promising technologies aboard suborbital rockets and other vehicles flown by commercial companies.
Early flight tests in 2013 sufficiently demonstrated the platform’s performance, earning CDI’s technology a spot on the International Space Station in 2016. But the flight testing didn’t end there. A rapid series of flights with Blue Origin, UP Aerospace, and Virgin Galactic put the platform through its paces, including numerous boosts and thruster firings, pyrotechnic shocks, and the forces of reentry and landing.
“Flight Opportunities was instrumental in our development,” said Dr. Scott Green, CDI’s co-founder and the platform’s principal investigator. “With five separate flight campaigns in just eight months, those tests allowed us to build up flight maturity and readiness so we could transition to deep space.”
The vibration isolation platform developed by Controlled Dynamics Inc., and used on the Deep Space Optical Communications experiment conducted numerous tests through NASA’s Flight Opportunities program, including this flight aboard Virgin Galactic’s VSS Unity in February 2019. Virgin Galactic The culmination of NASA’s investments in CDI’s vibration isolation platform was through its Technology Demonstration Missions program, which along with NASA’s SCaN (Space Communications and Navigation) program supported NASA’s Deep Space Optical Communications.
On Oct. 13, 2023, DSOC launched aboard the Psyche spacecraft, a mission managed by JPL. The CDI isolation platform provided DSOC with the active stabilization and precision pointing needed to successfully transmit a high-definition video of Taters the cat and other sample data from record-breaking distances in deep space.
“Active stabilization of the flight laser transceiver is required to help the project succeed in its goal to downlink high bandwidth data from millions of miles,” said Klipstein. “To do this, we need to measure our pointing and avoid bumping into the spacecraft while we are floating. The CDI struts gave us that capability.”
The Deep Space Optical Communications technology demonstration’s flight laser transceiver is shown at NASA’s Jet Propulsion Laboratory in Southern California in April 2021. The transceiver is mounted on an assembly of struts and actuators — developed by Controlled Dynamics Inc. — that stabilizes the optics from spacecraft vibrations. Several Space Technology Mission Directorate programs supported the vibration isolation technology’s development. NASA/JPL-Caltech Onward Toward Psyche
The Psyche spacecraft is expected to reach its namesake metal-rich asteroid located between Mars and Jupiter by August 2029. In the meantime, the DSOC project team is celebrating recognition as one of TIME’s Inventions of 2024 and expects the experiment to continue adding to its long list of goals met and exceeded in its first year.
By Nancy Pekar
NASA’s Flight Opportunities Program
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Last Updated Nov 14, 2024 EditorLoura Hall Related Terms
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By NASA
5 min read
Preparations for Next Moonwalk Simulations Underway (and Underwater)
NASA’s EMIT collected this hyperspectral image of the Amazon River in northern Brazil on June 30 as part of an effort to map global ecosystem biodiversity. The instrument was originally tasked with mapping minerals over deserts; its data is now being used in research on a diverse range of topics. NASA/JPL-Caltech The imaging spectrometer measures the colors of light reflected from Earth’s surface to study fields such as agriculture, hydrology, and climate science.
Observing our planet from the International Space Station since July 2022, NASA’s EMIT (Earth Surface Mineral Dust Source Investigation) mission is beginning its next act.
At first the imaging spectrometer was solely aimed at mapping minerals over Earth’s desert regions to help determine the cooling and heating effects that dust can have on regional and global climate. The instrument soon added another skill: pinpointing greenhouse gas emission sources, including landfills and fossil fuel infrastructure.
Following a mission extension this year, EMIT is now collecting data from regions beyond deserts, addressing topics as varied as agriculture, hydrology, and climate science.
Imaging spectrometers like EMIT detect the light reflected from Earth, and they separate visible and infrared light into hundreds of wavelength bands — colors, essentially. Scientists use patterns of reflection and absorption at different wavelengths to determine the composition of what the instrument is observing. The approach echoes Isaac Newton’s prism experiments in 1672, in which the physicist discovered that visible light is composed of a rainbow of colors.
Perched on the International Space Station, NASA’s EMIT can differentiate between types of vegetation to help researchers understand the distribution and traits of plant communities. The instrument collected this data over the mid-Atlantic U.S. on April 23.NASA/JPL-Caltech “Breakthroughs in optics, physics, and chemistry led to where we are today with this incredible instrument, providing data to help address pressing questions on our planet,” said Dana Chadwick, EMIT’s applications lead at NASA’s Jet Propulsion Laboratory in Southern California.
New Science Projects
In its extended mission, EMIT’s data will be the focus of 16 new projects under NASA’s Research Opportunities in Space and Earth Science (ROSES) program, which funds science investigations at universities, research institutions, and NASA.
For example, the U.S. Geological Survey (USGS) and the U.S. Department of Agriculture’s (USDA) Agricultural Research Service are exploring how EMIT can assess climate-smart agricultural practices. Those practices — winter cover crops and conservation tillage — involve protecting cropland during non-growing seasons with either living plants or dead plant matter to prevent erosion and manage nitrogen.
Imaging spectrometers are capable of gathering data on the distribution and characteristics of plants and plant matter, based on the patterns of light they reflect. The information can help agricultural agencies incentivize farmers to use sustainable practices and potentially help farmers manage their fields.
“We’re adding more accuracy and reducing error on the measurements we are supplying to end users,” said Jyoti Jennewein, an Agricultural Research Service research physical scientist based in Fort Collins, Colorado, and a project co-lead.
The USGS-USDA project is also informing analytical approaches for NASA’s future Surface Biology and Geology-Visible Shortwave Infrared mission. The satellite will cover Earth’s land and coasts more frequently than EMIT, with finer spatial resolution.
Looking at Snowmelt
Another new project will test whether EMIT data can help refine estimates of snowpack melting rates. Such an improvement could inform water management in states like California, where meltwater makes up the majority of the agricultural water supply.
Imaging spectrometers like EMIT measure the albedo of snow — the percentage of solar radiation it’s reflecting. What isn’t reflected is absorbed, so the observations indicate how much energy snow is taking in, which in turn helps with estimates of snow melt rates. The instruments also discern what’s affecting albedo: snow-grain size, dust or soot contamination, or both.
For this work, EMIT’s ability to measure beyond visible light is key. Ice is “pretty absorptive at near-infrared and the shortwave infrared wavelengths,” said Jeff Dozier, a University of California, Santa Barbara professor emeritus and the project’s principal investigator.
Other ROSES-funded projects focus on wildflower blooming, phytoplankton and carbon dynamics in inland waters, ecosystem biodiversity, and functional traits of forests.
Dust Impacts
Researchers with EMIT will continue to study the climate effects of dust. When lofted into the air by windstorms, darker, iron-filled dust absorbs the Sun’s heat and warms the surrounding air, while lighter-colored, clay-rich particles do the opposite. Scientists have been uncertain whether airborne dust has overall cooling or warming effects on the planet. Before EMIT, they could only assume the color of particles in a region.
The EMIT mission is “giving us lab-quality results, everywhere we need to know,” said Natalie Mahowald, the mission’s deputy principal investigator and an Earth system scientist at Cornell University in Ithaca, New York. Feeding the data into Earth system computer models, Mahowald expects to get closer to pinpointing dust’s climate impact as Earth warms.
Greenhouse Gas Detection
The mission will continue to identify point-source emissions of methane and carbon dioxide, the greenhouse gases most responsible for climate change, and observations are available through EMIT’s data portal and the U.S. Greenhouse Gas Center.
The EMIT team is also refining the software that identifies and measures greenhouse-gas plumes in the data, and they’re working to streamline the process with machine-learning automation. Aligning with NASA’s open science initiative, they are sharing code with public, private, and nonprofit organizations doing similar work.
“Making this work publicly accessible has fundamentally pushed the science of measuring point-source emissions forward and expanded the use of EMIT data,” said Andrew Thorpe, the JPL research technologist heading the EMIT greenhouse gas effort.
More About EMIT
The EMIT instrument was developed by NASA’s Jet Propulsion Laboratory, which is managed for the agency by Caltech in Pasadena, California. Launched to the International Space Station in July 2022, EMIT is on an extended three-year mission in which it’s supporting a range of research projects. EMIT’s data products are available at the NASA Land Processes Distributed Active Archive Center for use by other researchers and the public.
To learn more about the mission, visit:
https://earth.jpl.nasa.gov/emit/
How the new NISAR satellite will track Earth’s changing surface A planet-rumbling Greenland tsunami seen from above News Media Contacts
Andrew Wang / Jane J. Lee
Jet Propulsion Laboratory, Pasadena, Calif.
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Last Updated Nov 14, 2024 Related Terms
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