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By European Space Agency
On 4 December 2024, the European Space Agency (ESA) and the Indian Space Research Organisation (ISRO) signed an agreement that will see ESA provide ground station support to the missions in ISRO’s Gaganyaan human spaceflight programme.
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By European Space Agency
The SubOrbital Express-4 sounding rocket was successfully launched from the Esrange Space Center outside Kiruna, in the north of Sweden, at 06:00 CET yesterday morning.
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By NASA
Parallels between spaceflight and the aging process may extend to encompass frailty.
Figure Left: Venn diagram of differentially expressed frailty genes in rodent and human samples shows the common differentially expressed genes between the two species.
Figure Right: Schematic of the Inspiration4 experiments and samples.
This study relied on data from the OSDR, including 7 rodent spaceflight datasets, 2 human space analog datasets, astronaut data from the Japan Aerospace Exploration Agency (JAXA) and Inspiration4. Data on sarcopenia were mined from National Center for Biotechnology Information’s Gene Expression Omnibus. Spaceflight accelerates the symptoms of aging in astronaut bodies by inducing genomic instability, mitochondrial dysfunction, and increased inflammation. This is the first study to comprehensively examine biomarkers and pathways associated with spaceflight and terrestrial aging, frailty, and sarcopenia.
Main Findings:
Spaceflight induced notable changes in gene expression patterns related to frailty and muscle loss indicative of a frailty-like condition. Exposure to the space environment leads to changes related to inflammation, muscle wasting, and other age-related features observed in both mice and humans. Parallels between spaceflight and the aging process may extend to also encompass frailty. Impact: This work reveals the need for a frailty index to monitor development of frailty-related astronaut health risks during spaceflight. The results provide insights into potential avenues for developing countermeasures to combat frailty-related health risks for both astronauts and aging populations on Earth.
This study was part of the 44-article Space Omics and Medical Atlas (SOMA) package published in Nature. It demonstrates the effectiveness of open science combined with robust data submission, standards, and curation. The study began within and was organized through the Analysis Working Groups (AWGs) of NASA’s Open Science Data Repository (OSDR).
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By Space Force
U.S. Space Forces - Space supports NASA human space flight by planning, integrating, executing, and assessing space operations, providing continuous space situational awareness monitoring for the International Space Station and visiting spacecraft.
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By NASA
3 min read
Preparations for Next Moonwalk Simulations Underway (and Underwater)
Expedition 64 Flight Engineer Victor Glover of NASA sips on a water bag. The latest book marks our third effort to review available literature regarding the role of nutrition in astronaut health. In 2009, we reviewed the existing knowledge and history of human nutrition for spaceflight, with a key goal of identifying additional data that would be required before NASA could confidently reduce the risk of an inadequate food system or inadequate nutrition to as low as possible in support of human expeditions to the Moon or Mars. We used a nutrient-by-nutrient approach to address this effort, and we included a brief description of the space food systems during historical space programs.
In 2014, we published a second volume of the book, which was not so much a second edition, but rather a view of space nutrition from a different perspective. This volume updated research that had been published in the intervening 6 years and addressed space nutrition with a more physiological systems-based approach.
The current version is an expanded, updated version of that second book, providing both a systems approach overall, but also including details of nutrients and their roles within each system. As such, this book is divided into chapters based on physiological systems (e.g., bone, muscle, ocular); highlighted in each chapter are the nutrients associated with that particular system. We provide updated information on space food
systems and constraints of the same, and provide dietary intake data from International Space Station (ISS) astronauts.
We present data from ground-based analog studies, designed to mimic one or more conditions similar to those produced by spaceflight. Head-down tilt bed rest is a common analog of the general (and specifically musculoskeletal) disuse of spaceflight. Nutrition research from Antarctica relies on the associated confinement
and isolation, in addition to the lack of sunlight exposure during the winter months. Undersea habitats help expand our understanding of nutritional changes in a confined space with a hyperbaric atmosphere. We also review spaceflight research, including data from now “historical” flights on the Space Shuttle, data from the Russian space station Mir, and earlier space programs such as Apollo and Skylab. The ISS, now more than
20 years old, has provided (and continues to provide) a wealth of nutrition findings from extended-duration spaceflights of 4 to 12 months. We review findings from this platform as well, providing a comprehensive review of what is known regarding the role of human nutrition in keeping astronauts healthy.
With this latest book, we hope we have accurately captured the current state of the field of space food and nutrition, and that we have provided some guideposts for work that remains to be done to enable safe and successful human exploration beyond low-Earth orbit.
Human Adaptation to Spaceflight: The Role of Food and Nutrition – 2nd Edition
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Human Adaptation to Spaceflight: The Role of Food and Nutrition – 1st Edition
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Last Updated Oct 23, 2024 EditorRobert E. LewisLocationJohnson Space Center Related Terms
Human Health and Performance Keep Exploring Discover More Topics From NASA
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