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    • By NASA
      NASA’s Human Landing System (HLS) will transport the next astronauts that land on the Moon, including the first woman and first person of color, beginning with Artemis III. For safety and mission success, the landers and other equipment in development for NASA’s Artemis campaign must work reliably in the harshest of environments.
      The Hub for Innovative Thermal Technology Maturation and Prototyping (HI-TTeMP) lab at NASA’s Marshall Space Flight Center in Huntsville, Alabama, provides engineers with thermal analysis of materials that may be a prototype or in an early developmental stage using a vacuum chamber, back left, and a conduction chamber, right. NASA/Ken Hall Engineers at NASA’s Marshall Space Flight Center in Huntsville, Alabama, are currently testing how well prototype insulation for SpaceX’s Starship HLS will insulate interior environments, including propellant storage tanks and the crew cabin. Starship HLS will land astronauts on the lunar surface during Artemis III and Artemis IV.
      Marshall’s Hub for Innovative Thermal Technology Maturation and Prototyping (HI-TTeMP) laboratory provides the resources and tools for an early, quick-check evaluation of insulation materials destined for Artemis deep space missions.
      “Marshall’s HI-TTeMP lab gives us a key testing capability to help determine how well the current materials being designed for vehicles like SpaceX’s orbital propellant storage depot and Starship HLS, will insulate the liquid oxygen and methane propellants,” said HLS chief engineer Rene Ortega. “By using this lab and the expertise provided by the thermal engineers at Marshall, we are gaining valuable feedback earlier in the design and development process that will provide additional information before qualifying hardware for deep space missions.”
      A peek inside the conductive test chamber at NASA Marshall’s HI-TTeMP lab where thermal engineers design, set up, execute, and analyze materials destined for deep space to better understand how they will perform in the cold near-vacuum of space. NASA/Ken Hall On the Moon, spaceflight hardware like Starship HLS will face extreme temperatures. On the Moon’s south pole during lunar night, temperatures can plummet to -370 degrees Fahrenheit (-223 degrees Celsius). Elsewhere in deep space temperatures can range from roughly 250 degrees Fahrenheit (120 degrees Celsius) in direct sunlight to just above absolute zero in the shadows.
      There are two primary means of managing thermal conditions: active and passive. Passive thermal controls include materials such as insulation, white paint, thermal blankets, and reflective metals. Engineers can also design operational controls, such as pointing thermally sensitive areas of a spacecraft away from direct sunlight, to help manage extreme thermal conditions. Active thermal control measures that could be used include radiators or cryogenic coolers.
      Engineers use two vacuum test chambers in the lab to simulate the heat transfer effects of the deep space environment and to evaluate the thermal properties of the materials. One chamber is used to understand radiant heat, which directly warms an object in its path, such as when heat from the Sun shines on it. The other test chamber evaluates conduction by isolating and measuring its heat transfer paths.
      NASA engineers working in the HI-TTeMP lab not only design, set up, and run tests, they also provide insight and expertise in thermal engineering to assist NASA’s industry partners, such as SpaceX and other organizations, in validating concepts and models, or suggesting changes to designs. The lab is able to rapidly test and evaluate design updates or iterations.
      NASA’s HLS Program, managed by NASA Marshall, is charged with safely landing astronauts on the Moon as part of Artemis. NASA has awarded contracts to SpaceX for landing services for Artemis III and IV and to Blue Origin for Artemis V. Both landing services providers plan to transfer super-cold propellant in space to send landers to the Moon with full tanks.
      With Artemis, NASA will explore more of the Moon than ever before, learn how to live and work away from home, and prepare for future human exploration of Mars. NASA’s SLS (Space Launch System) rocket, exploration ground systems, and Orion spacecraft, along with the HLS, next-generation spacesuits, Gateway lunar space station, and future rovers are NASA’s foundation for deep space exploration.
      For more on HLS, visit: 
      https://www.nasa.gov/humans-in-space/human-landing-system
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      Corinne Beckinger 
      Marshall Space Flight Center, Huntsville, Ala. 
      256.544.0034  
      corinne.m.beckinger@nasa.gov 
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      2 Min Read Why NASA Is a Great Place to Launch Your Career 
      Students at NASA's Jet Propulsion Laboratory pose for photos around the laboratory wearing their eclipse glasses. Credits: NASA/JPL-Caltech  Recently recognized as the most prestigious internship program by Vault.com, NASA has empowered countless students and early-career professionals to launch careers in science, technology, engineering, and mathematics (STEM) fields. NASA interns make real contributions to space and science missions, making it one of the best places to start your career. 
      “NASA internships give students the chance to work on groundbreaking projects alongside experts, providing impactful opportunities for professional growth,” said Mike Kincaid, associate administrator for NASA’s Office of STEM Engagement. “Since starting my career as an intern at NASA’s Johnson Space Center in Houston, I’ve experienced firsthand how NASA creates lasting connections and open doors—not just for me, but for former interns who are now colleagues across the agency. These internships build STEM skills, confidence, and networks, preparing the next generation of innovators and leaders.” 
      NASA interns achieve impressive feats, from discovering new exoplanets to becoming astronauts and even winning Webby Awards for their science communication efforts. These valuable contributors play a crucial role in NASA’s mission to explore the unknown for the benefit of all. Many NASA employees start their careers as interns, a testament to the program’s lasting impact. 
      Students congratulate the 23rd astronaut class at NASA’s Johnson Space Center in Houston on March 5, 2024.NASA/Josh Valcarcel Additionally, NASA is recognized as one of America’s Best Employers for Women and one of America’s Best Employers for New Graduates by Forbes, reflecting the agency’s commitment to fostering a diverse and inclusive environment. NASA encourages people from underrepresented groups to apply, creating a diverse cohort of interns who bring a wide range of perspectives and ideas to the agency.  
      “My internship experience has been incredible. I have felt welcomed by everyone I’ve worked with, which has been so helpful as a Navajo woman as I’ve often felt like an outsider in male-dominated STEM spaces,” said Tara Roanhorse, an intern for NASA’s Office of STEM Engagement. 
      If you’re passionate about space, technology, and making a difference in the world, NASA’s internship program is the perfect place to begin your journey toward a fulfilling and impactful career.  
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    • By NASA
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      The mystery of why life uses molecules with specific orientations has deepened with a NASA-funded discovery that RNA — a key molecule thought to have potentially held the instructions for life before DNA emerged — can favor making the building blocks of proteins in either the left-hand or the right-hand orientation. Resolving this mystery could provide clues to the origin of life. The findings appear in research recently published in Nature Communications.
      Proteins are the workhorse molecules of life, used in everything from structures like hair to enzymes (catalysts that speed up or regulate chemical reactions). Just as the 26 letters of the alphabet are arranged in limitless combinations to make words, life uses 20 different amino acid building blocks in a huge variety of arrangements to make millions of different proteins. Some amino acid molecules can be built in two ways, such that mirror-image versions exist, like your hands, and life uses the left-handed variety of these amino acids. Although life based on right-handed amino acids would presumably work fine, the two mirror images are rarely mixed in biology, a characteristic of life called homochirality. It is a mystery to scientists why life chose the left-handed variety over the right-handed one.
      A diagram of left-handed and right-handed versions of the amino acid isovaline, found in the Murchison meteorite.NASA DNA (deoxyribonucleic acid) is the molecule that holds the instructions for building and running a living organism. However, DNA is complex and specialized; it “subcontracts” the work of reading the instructions to RNA (ribonucleic acid) molecules and building proteins to ribosome molecules. DNA’s specialization and complexity lead scientists to think that something simpler should have preceded it billions of years ago during the early evolution of life. A leading candidate for this is RNA, which can both store genetic information and build proteins. The hypothesis that RNA may have preceded DNA is called the “RNA world” hypothesis.
      If the RNA world proposition is correct, then perhaps something about RNA caused it to favor building left-handed proteins over right-handed ones. However, the new work did not support this idea, deepening the mystery of why life went with left-handed proteins.
      The experiment tested RNA molecules that act like enzymes to build proteins, called ribozymes. “The experiment demonstrated that ribozymes can favor either left- or right-handed amino acids, indicating that RNA worlds, in general, would not necessarily have a strong bias for the form of amino acids we observe in biology now,” said Irene Chen, of the University of California, Los Angeles (UCLA) Samueli School of Engineering, corresponding author of the Nature Communications paper.
      In the experiment, the researchers simulated what could have been early-Earth conditions of the RNA world. They incubated a solution containing ribozymes and amino acid precursors to see the relative percentages of the right-handed and left-handed amino acid, phenylalanine, that it would help produce. They tested 15 different ribozyme combinations and found that ribozymes can favor either left-handed or right-handed amino acids. This suggested that RNA did not initially have a predisposed chemical bias for one form of amino acids. This lack of preference challenges the notion that early life was predisposed to select left-handed-amino acids, which dominate in modern proteins.
      “The findings suggest that life’s eventual homochirality might not be a result of chemical determinism but could have emerged through later evolutionary pressures,” said co-author Alberto Vázquez-Salazar, a UCLA postdoctoral scholar and member of Chen’s research group.
      Earth’s prebiotic history lies beyond the oldest part of the fossil record, which has been erased by plate tectonics, the slow churning of Earth’s crust. During that time, the planet was likely bombarded by asteroids, which may have delivered some of life’s building blocks, such as amino acids. In parallel to chemical experiments, other origin-of-life researchers have been looking at molecular evidence from meteorites and asteroids.
      “Understanding the chemical properties of life helps us know what to look for in our search for life across the solar system,” said co-author Jason Dworkin, senior scientist for astrobiology at NASA’s Goddard Space Flight Center in Greenbelt, Maryland, and director of Goddard’s Astrobiology Analytical Laboratory.
      Dworkin is the project scientist on NASA’s OSIRIS-REx mission, which extracted samples from the asteroid Bennu and delivered them to Earth last year for further study.
      “We are analyzing OSIRIS-REx samples for the chirality (handedness) of individual amino acids, and in the future, samples from Mars will also be tested in laboratories for evidence of life including ribozymes and proteins,” said Dworkin.
      The research was supported by grants from NASA, the Simons Foundation Collaboration on the Origin of Life, and the National Science Foundation. Vázquez-Salazar acknowledges support through the NASA Postdoctoral Program, which is administered by Oak Ridge Associated Universities under contract with NASA.
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      Last Updated Nov 21, 2024 EditorWilliam SteigerwaldContactNancy N. Jonesnancy.n.jones@nasa.govLocationGoddard Space Flight Center Related Terms
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