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By NASA
A host of scientific investigations await the crew of NASA’s SpaceX Crew-11 mission during their long-duration expedition aboard the International Space Station. NASA astronauts Zena Cardman and Mike Fincke, and JAXA (Japan Aerospace Exploration Agency) astronaut Kimiya Yui, are set to study plant cell division and microgravity’s effects on bacteria-killing viruses, as well as perform experiments to produce a higher volume of human stem cells and generate on-demand nutrients.
Here are details on some of the research scheduled during the Crew-11 mission:
Making more stem cells
Cultures of stem cells grown in 2D on Earth, left, and as 3D spheres in simulated microgravity on Earth.BioServe A stem cell investigation called StemCellEx-IP1 evaluates using microgravity to produce large numbers of induced pluripotent stem cells. Made by reprogramming skin or blood cells, these stem cells can transform into any type of cell in the body and are used in regenerative medicine therapies for many diseases. However, producing enough cells on the ground is a challenge.
Researchers plan to use the microgravity environment aboard the space station to demonstrate whether generating 1,000 times more cells is possible and whether these cells are of higher quality and better for clinical use than those made on Earth. If proven, this could significantly improve future patient outcomes.
“This type of stem cell research is a chance to find treatments and maybe even cures for diseases that currently have none,” said Tobias Niederwieser of BioServe Space Technologies, which developed the investigation. “This represents an incredible potential to make life here on Earth better for all of us. We can take skin or blood cells from a patient, convert them into stem cells, and produce custom cell-therapy with little risk for rejection, as they are the person’s own cells.”
Alternative to antibiotics
Genes in Space-12 student investigators Isabella Chuang, left, and Julia Gross, middle, with mentor Kayleigh Ingersoll Omdahl.Genes in Space Genes in Space is a series of competitions in which students in grades 7 through 12 design DNA experiments that are flown to the space station. Genes in Space-12 examines the effects of microgravity on interactions between certain bacteria and bacteriophages, which are viruses that infect and kill bacteria. Bacteriophages already are used to treat bacterial infections on Earth.
“Boeing and miniPCR bio co-founded this competition to bring real-world scientific experiences to the classroom and promote molecular biology investigations on the space station,” said Scott Copeland of Boeing, and co-founder of Genes in Space. “This
investigation could establish a foundation for using these viruses to treat bacterial infections in space, potentially decreasing the dependence on antibiotics.”
“Previous studies indicate that bacteria may display increased growth rates and virulence in space, while the antibiotics used to combat them may be less effective,” said Dr. Ally Huang, staff scientist at miniPCR bio. “Phages produced in space could have profound implications for human health, microbial control, and the sustainability of long-duration remote missions. Phage therapy tools also could revolutionize how we manage bacterial infections and microbial ecosystems on Earth.”
Edible organisms
A purple, pre-incubation BioNutrients-3 bag, left, and a pink bag, right, which has completed incubation, on a purple and pink board used for comparison.NASA Some vitamins and nutrients in foods and supplements lose their potency during prolonged storage, and insufficient intake of even a single nutrient can lead to serious diseases, such as a vitamin C deficiency, causing scurvy. The BioNutrients-3 experiment builds on previous investigations looking at ways to produce on-demand nutrients in space using genetically engineered organisms that remain viable for years. These include yogurt and a yeast-based beverage made from yeast strains previously tested aboard station, as well as a new, engineered co-culture that produces multiple nutrients in one sample bag.
“BioNutrients-3 includes multiple food safety features, including pasteurization to kill microorganisms in the sample and a demonstration of the feasibility of using a sensor called E-Nose that simulates an ultra-sensitive nose to detect pathogens,” said Kevin Sims, project manager at NASA’s Ames Research Center in California’s Silicon Valley.
Another food safety feature is a food-grade pH indicator to track bacterial growth.
“These pH indicators help the crew visualize the progress of the yogurt and kefir samples,” Sims said. “As the organisms grow, they generate lactic acid, which lowers the pH and turns the indicator pink.”
The research also features an investigation of yogurt passage, which seeds new cultures using a bit of yogurt from a finished bag, much like maintaining a sourdough bread starter. This method could sustain a culture over multiple generations, eliminating concerns about yogurt’s shelf life during a mission to the Moon or Mars while reducing launch mass.
Understanding cell division
Cells of green algae dividing.University of Toyama The JAXA Plant Cell Division investigation examines how microgravity affects cell division in green algae and a strain of cultured tobacco cells. Cell division is a fundamental element of plant growth, but few studies have examined it in microgravity.
“The tobacco cells divide frequently, making the process easy to observe,” said Junya Kirima of JAXA. “We are excited to reveal the effects of the space environment on plant cell division and look forward to performing time-lapse live imaging of it aboard the space station.”
Understanding this process could support the development of better methods for growing plants for food in space, including on the Moon and Mars. This investigation also could provide insight to help make plant production systems on Earth more efficient.
For nearly 25 years, people have lived and worked continuously aboard the International Space Station, advancing scientific knowledge and conducting critical research for the benefit of humanity and our home planet. Space station research supports the future of human spaceflight as NASA looks toward deep space missions to the Moon under the Artemis campaign and in preparation for future human missions to Mars, as well as expanding commercial opportunities in low Earth orbit and beyond.
Learn more about the International Space Station at:
https://www.nasa.gov/station
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By NASA
4 min read
Preparations for Next Moonwalk Simulations Underway (and Underwater)
An international team of astronomers has uncovered new evidence to explain how pulsing remnants of exploded stars interact with surrounding matter deep in the cosmos, using observations from NASA’s IXPE (Imaging X-ray Polarimetry Explorer) and other telescopes.
Scientists based in the U.S., Italy, and Spain, set their sights on a mysterious cosmic duo called PSR J1023+0038, or J1023 for short. The J1023 system is comprised of a rapidly rotating neutron star feeding off of its low-mass companion star, which has created an accretion disk around the neutron star. This neutron star is also a pulsar, emitting powerful twin beams of light from its opposing magnetic poles as it rotates, spinning like a lighthouse beacon.
The J1023 system is rare and valuable to study because the pulsar transitions clearly between its active state, in which it feeds off its companion star, and a more dormant state, when it emits detectable pulsations as radio waves. This makes it a “transitional millisecond pulsar.”
An artist’s illustration depicting the central regions of the binary system PSR J1023+0038, including the pulsar, the inner accretion disc and the pulsar wind. Credit: Marco Maria Messa, University of Milan/INAF-OAB; Maria Cristina Baglio, INAF-OAB “Transitional millisecond pulsars are cosmic laboratories, helping us understand how neutron stars evolve in binary systems,” said researcher Maria Cristina Baglio of the Italian National Institute of Astrophysics (INAF) Brera Observatory in Merate, Italy, and lead author of a paper in The Astrophysical Journal Letters illustrating the new findings.
The big question for scientists about this pulsar system was: Where do the X-rays originate? The answer would inform broader theories about particle acceleration, accretion physics, and the environments surrounding neutron stars across the universe.
The source surprised them: The X-rays came from the pulsar wind, a chaotic stew of gases, shock waves, magnetic fields, and particles accelerated near the speed of light, that hits the accretion disk.
To determine this, astronomers needed to measure the angle of polarization in both X-ray and optical light. Polarization is a measure of how organized light waves are. They looked at X-ray polarization with IXPE, the only telescope capable of making this measurement in space, and comparing it with optical polarization from the European Southern Observatory’s Very Large Telescope in Chile. IXPE launched in Dec. 2021 and has made many observations of pulsars, but J1023 was the first system of its kind that it explored.
NASA’s NICER (Neutron star Interior Composition Explorer) and Neil Gehrels Swift Observatory provided valuable observations of the system in high-energy light. Other telescopes contributing data included the Karl G. Jansky Very Large Array in Magdalena, New Mexico.
The result: scientists found the same angle of polarization across the different wavelengths.
“That finding is compelling evidence that a single, coherent physical mechanism underpins the light we observe,” said Francesco Coti Zelati of the Institute of Space Sciences in Barcelona, Spain, co-lead author of the findings.
This interpretation challenges the conventional wisdom about neutron star emissions of radiation in binary systems, the researchers said. Previous models had indicated that the X-rays come from the accretion disk, but this new study shows they originate with the pulsar wind.
“IXPE has observed many isolated pulsars and found that the pulsar wind powers the X-rays,” said NASA Marshall astrophysicist Philip Kaaret, principal investigator for IXPE at NASA’s Marshall Space Flight Center in Huntsville, Alabama. “These new observations show that the pulsar wind powers most of the energy output of the system.”
Astronomers continue to study transitional millisecond pulsars, assessing how observed physical mechanisms compare with those of other pulsars and pulsar wind nebulae. Insights from these observations could help refine theoretical models describing how pulsar winds generate radiation – and bring researchers one step closer, Baglio and Coti Zelati agreed, to fully understanding the physical mechanisms at work in these extraordinary cosmic systems.
More about IXPE
IXPE, which continues to provide unprecedented data enabling groundbreaking discoveries about celestial objects across the universe, is a joint NASA and Italian Space Agency mission with partners and science collaborators in 12 countries. IXPE is led by NASA’s Marshall Space Flight Center in Huntsville, Alabama. BAE Systems, Inc., headquartered in Falls Church, Virginia, manages spacecraft operations together with the University of Colorado’s Laboratory for Atmospheric and Space Physics in Boulder. Learn more about IXPE’s ongoing mission here:
https://www.nasa.gov/ixpe
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Last Updated Jul 15, 2025 EditorBeth RidgewayContactCorinne M. Beckingercorinne.m.beckinger@nasa.govLocationMarshall Space Flight Center Related Terms
IXPE (Imaging X-ray Polarimetry Explorer) Marshall Astrophysics Marshall Science Research & Projects Marshall Space Flight Center Explore More
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By NASA
Scientists predict one of the major surveys by NASA’s upcoming Nancy Grace Roman Space Telescope may reveal around 100,000 celestial blasts, ranging from exploding stars to feeding black holes. Roman may even find evidence of some of the universe’s first stars, which are thought to completely self-destruct without leaving any remnant behind.
This simulation showcases the dynamic universe as NASA’s Nancy Grace Roman Space Telescope could see it over the course of its five-year primary mission. The video sparkles with synthetic supernovae from observations of the OpenUniverse simulated universe taken every five days (similar to the expected cadence of Roman’s High-Latitude Time-Domain Survey, which OpenUniverse simulates in its entirety). On top of the static sky of stars in the Milky Way and other galaxies, more than a million exploding stars flare into visibility and then slowly fade away. To highlight the dynamic physics happening and for visibility at this scale, the true brightness of each transient event has been magnified by a factor of 10,000 and no background light has been added to the simulated images. The video begins with Roman’s full field of view, which represents a single pointing of Roman’s camera, and then zooms into one square.Credit: NASA’s Goddard Space Flight Center and M. Troxel Cosmic explosions offer clues to some of the biggest mysteries of the universe. One is the nature of dark energy, the mysterious pressure thought to be accelerating the universe’s expansion.
“Whether you want to explore dark energy, dying stars, galactic powerhouses, or probably even entirely new things we’ve never seen before, this survey will be a gold mine,” said Benjamin Rose, an assistant professor at Baylor University in Waco, Texas, who led a study about the results. The paper is published in The Astrophysical Journal.
Called the High-Latitude Time-Domain Survey, this observation program will scan the same large region of the cosmos every five days for two years. Scientists will stitch these observations together to create movies that uncover all sorts of cosmic fireworks.
Chief among them are exploding stars. The survey is largely geared toward finding a special class of supernova called type Ia. These stellar cataclysms allow scientists to measure cosmic distances and trace the universe’s expansion because they peak at about the same intrinsic brightness. Figuring out how fast the universe has ballooned during different cosmic epochs offers clues to dark energy.
This landscape of “mountains” and “valleys” speckled with glittering stars is actually the edge of a nearby, young, star-forming region called NGC 3324 in the Carina Nebula. Captured in infrared light by NASA’s new James Webb Space Telescope, this image reveals for the first time previously invisible areas of star birth.Credit: NASA, ESA, CSA, and STScI In the new study, scientists simulated Roman’s entire High-Latitude Time-Domain Survey. The results suggest Roman could see around 27,000 type Ia supernovae—about 10 times more than all previous surveys combined.
Beyond dramatically increasing our total sample of these supernovae, Roman will push the boundaries of how far back in time we can see them. While most of those detected so far occurred within approximately the last 8 billion years, Roman is expected to see vast numbers of them earlier in the universe’s history, including more than a thousand that exploded more than 10 billion years ago and potentially dozens from as far back as 11.5 billion years. That means Roman will almost certainly set a new record for the farthest type Ia supernova while profoundly expanding our view of the early universe and filling in a critical gap in our understanding of how the cosmos has evolved over time.
“Filling these data gaps could also fill in gaps in our understanding of dark energy,” Rose said. “Evidence is mounting that dark energy has changed over time, and Roman will help us understand that change by exploring cosmic history in ways other telescopes can’t.”
But type Ia supernovae will be hidden among a much bigger sample of exploding stars Roman will see once it begins science operations in 2027. The team estimates Roman will also spot about 60,000 core-collapse supernovae, which occur when a massive star runs out of fuel and collapses under its own weight.
That’s different from type Ia supernovae, which originate from binary star systems that contain at least one white dwarf — the small, hot core remnant of a Sun-like star — siphoning material from a companion star. Core-collapse supernovae aren’t as useful for dark energy studies as type Ias are, but their signals look similar from halfway across the cosmos.
“By seeing the way an object’s light changes over time and splitting it into spectra — individual colors with patterns that reveal information about the object that emitted the light—we can distinguish between all the different types of flashes Roman will see,” said Rebekah Hounsell, an assistant research scientist at the University of Maryland-Baltimore County working at NASA’s Goddard Space Flight Center in Greenbelt, Maryland and a co-author of the study.
“With the dataset we’ve created, scientists can train machine-learning algorithms to distinguish between different types of objects and sift through Roman’s downpour of data to find them,” Hounsell added. “While searching for type Ia supernovae, Roman is going to collect a lot of cosmic ‘bycatch’—other phenomena that aren’t useful to some scientists, but will be invaluable to others.”
Hidden Gems
Thanks to Roman’s large, deep view of space, scientists say the survey should also unearth extremely rare and elusive phenomena, including even scarcer stellar explosions and disintegrating stars.
Upon close approach to a black hole, intense gravity can shred a star in a so-called tidal disruption event. The stellar crumbs heat up as they swirl around the black hole, creating a glow astronomers can see from across vast stretches of space-time. Scientists think Roman’s survey will unveil 40 tidal disruption events, offering a chance to learn more about black hole physics.
The team also estimates Roman will find about 90 superluminous supernovae, which can be 100 times brighter than a typical supernova. They pack a punch, but scientists aren’t completely sure why. Finding more of them will help astronomers weigh different theories.
Even rarer and more powerful, Roman could also detect several kilonovae. These blasts occur when two neutron stars — extremely dense cores leftover from stars that exploded as supernovae — collide. To date, there has been only one definitive kilonova detection. The team estimates Roman could spot five more.
NASA’s Roman Space Telescope will survey the same areas of the sky every few days following its launch in May 2027. Researchers will mine these data to identify kilonovae – explosions that happen when two neutron stars or a neutron star and a black hole collide and merge. When these collisions happen, a fraction of the resulting debris is ejected as jets, which move near the speed of light. The remaining debris produces hot, glowing, neutron-rich clouds that forge heavy elements, like gold and platinum. Roman’s extensive data will help astronomers better identify how often these events occur, how much energy they give off, and how near or far they are.Credit: NASA, ESA, J. Olmsted (STScI) That would help astronomers learn much more about these mysterious events, potentially including their fate. As of now, scientists are unsure whether kilonovae result in a single neutron star, a black hole, or something else entirely.
Roman may even spot the detonations of some of the first stars that formed in the universe. These nuclear furnaces were giants, up to hundreds of times more massive than our Sun, and unsullied by heavy elements that hadn’t yet formed.
They were so massive that scientists think they exploded differently than modern massive stars do. Instead of reaching the point where a heavy star today would collapse, intense gamma rays inside the first stars may have turned into matter-antimatter pairs (electrons and positrons). That would drain the pressure holding the stars up until they collapsed, self-destructing in explosions so powerful they’re thought to leave nothing behind.
So far, astronomers have found about half a dozen candidates of these “pair-instability” supernovae, but none have been confirmed.
“I think Roman will make the first confirmed detection of a pair-instability supernova,” Rose said — in fact the study suggests Roman will find more than 10. “They’re incredibly far away and very rare, so you need a telescope that can survey a lot of the sky at a deep exposure level in near-infrared light, and that’s Roman.”
A future rendition of the simulation could include even more types of cosmic flashes, such as variable stars and active galaxies. Other telescopes may follow up on the rare phenomena and objects Roman discovers to view them in different wavelengths of light to study them in more detail.
“Roman’s going to find a whole bunch of weird and wonderful things out in space, including some we haven’t even thought of yet,” Hounsell said. “We’re definitely expecting the unexpected.”
For more information about the Roman Space Telescope visit www.nasa.gov/roman.
The Nancy Grace Roman Space Telescope is managed at NASA’s Goddard Space Flight Center in Greenbelt, Maryland, with participation by NASA’s Jet Propulsion Laboratory in Southern California; Caltech/IPAC in Pasadena, California; the Space Telescope Science Institute in Baltimore; and a science team comprising scientists from various research institutions. The primary industrial partners are BAE Systems Inc. in Boulder, Colorado; L3Harris Technologies in Rochester, New York; and Teledyne Scientific & Imaging in Thousand Oaks, California.
By Ashley Balzer
NASA’s Goddard Space Flight Center, Greenbelt, Md.
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Last Updated Jul 15, 2025 EditorAshley BalzerContactAshley Balzerashley.m.balzer@nasa.gov Related Terms
Nancy Grace Roman Space Telescope Astrophysics Black Holes Dark Energy Galaxies, Stars, & Black Holes Galaxies, Stars, & Black Holes Research Goddard Space Flight Center Science & Research Stars Supernovae The Universe Explore More
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By NASA
The Axiom Mission 4 crew launched on June 25, 2025, aboard a SpaceX Dragon spacecraft to the International Space Station from NASA’s Kennedy Space Center in Florida. From left to right: Tibor Kapu of Hungary, ISRO (Indian Space Research Organization) astronaut Shubhanshu Shukla, former NASA astronaut Peggy Whitson, and ESA (European Space Agency) astronaut Sławosz Uznański-Wiśniewski of Poland (Credit: Axiom Space). The NASA-supported fourth private astronaut mission to the International Space Station, Axiom Mission 4, completed its flight as part of the agency’s efforts to demonstrate demand and build operational knowledge for future commercial space stations.
The four-person crew safely returned to Earth, splashing down off the coast of California at 5:31 a.m. EDT on Tuesday, aboard a SpaceX Dragon spacecraft. Teams aboard SpaceX recovery vessels retrieved the spacecraft and astronauts.
Peggy Whitson, former NASA astronaut and director of human spaceflight at Axiom Space, ISRO (Indian Space Research Organization) astronaut Shubhanshu Shukla, and ESA (European Space Agency) project astronaut Sławosz Uznański-Wiśniewski of Poland, and Hungarian to Orbit (HUNOR) astronaut Tibor Kapu of Hungary, completed about two and a half weeks in space.
The Axiom Mission 4 crew launched at 2:31 a.m. on June 25, on a Falcon 9 rocket from NASA’s Kennedy Space Center in Florida. Approximately 28 hours later, Dragon docked to the space-facing port of the space station’s Harmony module. The astronauts undocked at 7:15 a.m. on July 14, to begin the trip home.
The crew conducted microgravity research, educational outreach, and commercial activities. The spacecraft will return to Florida for inspection and processing at SpaceX’s refurbishing facilities. Throughout their mission, the astronauts conducted about 60 science experiments, and returned science, including NASA cargo, back to Earth.
A collaboration between NASA and ISRO allowed Axiom Mission 4 to deliver on a commitment highlighted by President Trump and Indian Prime Minister Narendra Modi to send the first ISRO astronaut to the station. The space agencies participated in five joint science investigations and two in-orbit science, technology, engineering, and mathematics demonstrations. NASA and ISRO have a long-standing relationship built on a shared vision to advance scientific knowledge and expand space collaboration.
The private mission also carried the first astronauts from Poland and Hungary to stay aboard the space station.
The International Space Station is a springboard for developing a low Earth orbit economy. NASA’s goal is to achieve a strong economy off the Earth where the agency can purchase services as one of many customers to meet its science and research objectives in microgravity. NASA’s commercial strategy for low Earth orbit provides the government with reliable and safe services at a lower cost, enabling the agency to focus on Artemis missions to the Moon in preparation for Mars while also continuing to use low Earth orbit as a training and proving ground for those deep space missions.
Learn more about NASA’s commercial space strategy at:
https://www.nasa.gov/commercial-space
News Media Contacts:
Claire O’Shea
Headquarters, Washington
202-358-1100
claire.a.o’shea@nasa.gov
Anna Schneider
Johnson Space Center, Houston
281-483-5111
anna.c.schneider@nasa.gov
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By NASA
Melissa Harris’ official NASA portrait. NASA/Robert Markowitz With over 25 years of experience in human spaceflight programs, Melissa Harris has contributed to numerous programs and projects during key moments in NASA’s history. As the life cycle lead and Independent Review Team review manager for the Commercial Low Earth Orbit Development Program, she guides the agency through development initiatives leading to a new era of space exploration.
Harris grew up near NASA’s Johnson Space Center in Houston and spent time exploring the center and trying on astronaut helmets. She later earned her bachelor’s degree in legal studies from the University of Houston, master and subject matter expert certifications in configuration management, and ISO 9001 Lead Auditors Certification. When the opportunity arose, she jumped at the chance to join the International Space Station Program.
Harris (right) and her twin sister, Yvonne (left), at the Artemis I launch. Image courtesy of Melissa Harris Starting as a board specialist, Harris spent eight years supporting the space station program boards, panels, and flight reviews. Other areas of support included the International Space Station Mission Evaluation Room and the EVA Crew Systems and Robotics Division managing changes for the acquisition and building of mockups in the Neutral Buoyancy Laboratory and Space Vehicle Mockup Facility in Houston. She then took a leap to join the Constellation Program, developing and overseeing program and project office processes and procedures. Harris then transitioned to the Extravehicular Activity (EVA) Project Office where she was a member of the EVA 23 quality audit team tasked with reviewing data to determine the cause of an in-orbit failure. She also contributed to the Orion Program and Artemis campaign. After spending two years at Axiom Space, Harris returned to NASA and joined the commercial low Earth orbit team.
Harris said the biggest lesson she has learned during her career is that “there are always ups and downs and not everything works out, but if you just keep going and at the end of the day see that the hard work and dedication has paid off, it is always the proudest moment.”
Her dedication led to a nomination for the Stellar Award by the Rotary National Award for Space Achievement Foundation.
Harris and her son, Tyler, at the Rotary National Award Banquet in 2024.Image courtesy of Melissa Harris Harris’ favorite part of her role at NASA is working “closely with brilliant minds” and being part of a dedicated and hard-working team that contributes to current space programs while also planning for future programs. Looking forward, she anticipates witnessing the vision and execution of a self-sustaining commercial market in low Earth orbit come to fruition.
Outside of work, Harris enjoys being with family, whether cooking on the back porch, over a campfire, or traveling both in and out of the country. She has been married for 26 years to her high school sweetheart, Steve, and has one son, Tyler. Her identical twin sister, Yvonne, also works at Johnson.
Harris and her twin sister Yvonne dressed as Mark and Scott Kelly for Halloween in 2024.Image courtesy of Melissa Harris Learn more about NASA’s Commercial Low Earth Orbit Development Program at:
www.nasa.gov/commercialspacestations
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