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By NASA
5 min read
Preparations for Next Moonwalk Simulations Underway (and Underwater)
Astronaut Jeanette Epps extracts DNA samples from bacteria colonies for genomic analysis aboard the International Space Station’s Harmony module.NASA In an effort to learn more about astronaut health and the effects of space on the human body, NASA is conducting a new experiment aboard the International Space Station to speed up the detection of antibiotic-resistant bacteria, thus improving the health safety not only of astronauts but patients back on Earth.
Infections caused by antibiotic-resistant bacteria can be difficult or impossible to treat, making antibiotic resistance a leading cause of death worldwide and a global health concern.
Future astronauts visiting the Moon or Mars will need to rely on a pre-determined supply of antibiotics in case of illness. Ensuring those antibiotics remain effective is an important safety measure for future missions.
The Genomic Enumeration of Antibiotic Resistance in Space (GEARS) experiment, which is managed by NASA’s Ames Research Center in California’s Silicon Valley, involves astronauts swabbing interior surfaces across the space station and testing those samples for evidence of antibiotic-resistant bacteria, and in particular Enterococcus faecalis, a type of bacteria commonly found in the human body. The experiment is the first step in a series of work that seeks to better understand how organisms grow in a space environment, and how those similarities and differences might help improve research back on Earth.
“Enterococcus is a type of organism that’s been with us since our ancestors crawled out of the ocean, and is a core member of the human gut,” said Christopher Carr, assistant professor at the Georgia Institute of Technology and co-principal investigator of GEARS. “It’s able to survive inside and outside of its host, which has allowed it to become the second highest leading cause of hospital-acquired infections. We want to understand how this type of organism is adapting to the space environment.”
The GEARS experiment seeks to improve the detection and identification of these bacteria, building on existing efforts to understand what organisms grow on the station’s surfaces.
“We’ve been monitoring the surfaces of the space station since 2000, but this experiment will give us insight beyond the identities of present organisms, which is currently all that is used for risk assessment,” said Sarah Wallace, a microbiologist at NASA’s Johnson Space Center in Houston and co-principal investigator of GEARS. “With the station orbiting close to Earth, it’s a low-risk space to evaluate and learn more about the frequency of this bacteria and how it responds to the space environment so we can apply this understanding to missions to the Moon and Mars, where resupplies are more complex.”
Over the next year, astronauts will swab parts of the station and analyze samples by adding an antibiotic to the medium in which the samples will grow. The results will reveal where this and other resistant bacteria are growing and whether they can persist or spread across the station.
I hope we can shine a light on rapidly analyzing bacteria: if we can do this in space, we can do it on Earth, too.
Sarah WAllace
NASA Microbiologist
The experiment was originally launched to the ISS on the 30th SpaceX commercial resupply services (CRS) mission in March 2024, and the first round of GEARS testing turned up surprising results: very few resistant bacteria colonies, none of which were E. faecalis. This bodes well for the threat of antibiotic resistance in space.
“There was some cleaning done before swabbing the station, which may have removed some bacteria,” said Carr. To better understand how and where risky bacteria may live, the astronauts paused some cleaning before the second round of swabbing.
“We want the astronauts to have a clean environment, but we also want to test those high-touch areas, so they intentionally and briefly avoided cleaning some areas so we can understand how bacteria may grow or spread on the station.”
This experiment is the first study to perform metagenomic sequencing in space, a method that analyzes all the genetic material in a sample to identify and characterize all organisms that are present, an important research and medical diagnostic capability for future deep space missions.
The GEARS team hopes to create a rapid workflow to analyze bacteria samples, reducing the time between swabbing and test results from days to hours. That workflow could be applied in hospitals and make a huge impact when treating hospital-acquired infections from antibiotic-resistant microbes.
The result could save lives – more than 35,000 people die each year as a result of antibiotic-resistant infections. The issue is personal to Wallace, who lost a family member to a hospital-acquired infection.
“It’s not that uncommon: so many people have experienced this kind of loss,” said Wallace. “A method to give an answer in a matter of hours is huge and profound. It’s my job to keep the crew healthy, but we’re also passionate about bringing that work back down to Earth. I hope we can shine a light on rapidly analyzing bacteria: if we can do this in space, we can do it on Earth, too.”
Genomic Enumeration of Antibiotic Resistance in Space (GEARS) was funded by the Biological and Physical Sciences Space Biology Program, with pioneering funding and support from the Mars Campaign office.
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Last Updated Feb 19, 2025 Related Terms
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2 min read 2024 Annual Highlights of Results from the International Space Station Science
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By NASA
Official crew portrait for NASA’s SpaceX Crew-10 mission with NASA astronauts Anne McClain and Nichole Ayers, JAXA (Japan Aerospace Exploration Agency) astronaut Takuya Onishi, and Roscosmos cosmonaut Kirill Peskov.Credit: NASA NASA and its partners will discuss the upcoming Expedition 73 mission aboard the International Space Station during a pair of news conferences on Monday, Feb. 24, from the agency’s Johnson Space Center in Houston.
Mission leadership will participate in an overview news conference at 2 p.m. EST live on NASA+, covering preparations for NASA’s SpaceX Crew-10 launch in March and the agency’s crew member rotation launch on Soyuz in April. Learn how to watch NASA content through a variety of platforms, including social media.
NASA also will host a crew news conference at 4 p.m. and provide coverage on NASA+, followed by individual crew member interviews beginning at 5 p.m. This is the final media opportunity with Crew-10 before the crew members travel to NASA’s Kennedy Space Center in Florida for launch.
The Crew-10 mission, targeted to launch Wednesday, March 12, will carry NASA astronauts Anne McClain and Nichole Ayers, JAXA (Japan Aerospace Exploration Agency) astronaut Takuya Onishi, and Roscosmos cosmonaut Kirill Peskov to the orbiting laboratory.
NASA astronaut Jonny Kim, scheduled to launch to the space station on the Soyuz MS-27 spacecraft no earlier than April 8, also will participate in the crew briefing and interviews. Kim will be available again on Tuesday, March 18, for limited virtual interviews prior to launch. NASA will provide additional details on that opportunity when available.
For the Crew-10 mission, a SpaceX Falcon 9 rocket and Dragon spacecraft will launch from Launch Complex 39A at NASA Kennedy. The three-person crew of Soyuz MS-27, including Kim and Roscosmos cosmonauts Sergey Ryzhikov and Alexey Zubritsky, will launch from the Baikonur Cosmodrome in Kazakhstan.
United States-based media seeking to attend in person must contact the NASA Johnson newsroom no later than 5 p.m. on Friday, Feb. 21, at 281-483-5111 or at jsccommu@mail.nasa.gov. U.S. and international media interested in participating by phone must contact NASA Johnson by 9:45 a.m. the day of the event.
U.S. and international media seeking remote interviews with the crew must submit requests to the NASA Johnson newsroom by 5 p.m. on Feb. 21. A copy of NASA’s media accreditation policy is available online.
Briefing participants include (all times Eastern and subject to change based on real-time operations):
2 p.m.: Expedition 73 Overview News Conference
Ken Bowersox, associate administrator, Space Operations Mission Directorate at NASA Headquarters in Washington Steve Stich, manager, NASA’s Commercial Crew Program, NASA Kennedy Bill Spetch, operations integration manager, NASA’s International Space Station Program, NASA Johnson William Gerstenmaier, vice president, Build & Flight Reliability, SpaceX Mayumi Matsuura, vice president and director general, Human Spaceflight Technology Directorate, JAXA 4 p.m.: Expedition 73 Crew News Conference
Jonny Kim, Soyuz MS-27 flight engineer, NASA Anne McClain, Crew-10 spacecraft commander, NASA Nichole Ayers, Crew-10 pilot, NASA Takuya Onishi, Crew-10 mission specialist, JAXA Kirill Peskov, Crew-10 mission specialist, Roscosmos 5 p.m.: Crew Individual Interview Opportunities
Crew-10 members and Kim available for a limited number of interviews Official portrait of NASA astronaut Jonny Kim, who will serve as a flight engineer during Expedition 73.Credit: NASA Kim is making his first spaceflight after selection as part of the 2017 NASA astronaut class. A native of Los Angeles, Kim is a U.S. Navy lieutenant commander and dual designated naval aviator and flight surgeon. Kim also served as an enlisted Navy SEAL. He holds a bachelor’s degree in Mathematics from the University of San Diego and a medical degree from Harvard Medical School in Boston. He completed his internship with the Harvard Affiliated Emergency Medicine Residency at Massachusetts General Hospital and Brigham and Women’s Hospital. After completing the initial astronaut candidate training, Kim supported mission and crew operations in various roles, including the Expedition 65 lead operations officer, T-38 operations liaison, and space station capcom chief engineer. Follow @jonnykimusa on X and @jonnykimusa on Instagram.
Selected by NASA as an astronaut in 2013, this will be McClain’s second spaceflight. A colonel in the U.S. Army, she earned her bachelor’s degree in Mechanical Engineering from the U.S. Military Academy at West Point, New York, and holds master’s degrees in Aerospace Engineering, International Security, and Strategic Studies. The Spokane, Washington, native was an instructor pilot in the OH-58D Kiowa Warrior helicopter and is a graduate of the U.S. Naval Test Pilot School in Patuxent River, Maryland. McClain has more than 2,300 flight hours in 24 rotary and fixed-wing aircraft, including more than 800 in combat, and was a member of the U.S. Women’s National Rugby Team. On her first spaceflight, McClain spent 204 days as a flight engineer during Expeditions 58 and 59, and completed two spacewalks, totaling 13 hours and 8 minutes. Since then, she has served in various roles, including branch chief and space station assistant to the chief of NASA’s Astronaut Office. Follow @astroannimal on X and @astro_annimal on Instagram.
The Crew-10 mission will be the first spaceflight for Ayers, who was selected as a NASA astronaut in 2021. Ayers is a major in the U.S. Air Force and the first member of NASA’s 2021 astronaut class named to a crew. The Colorado native graduated from the Air Force Academy in Colorado Springs with a bachelor’s degree in Mathematics and a minor in Russian, where she was a member of the academy’s varsity volleyball team. She later earned a master’s in Computational and Applied Mathematics from Rice University in Houston. Ayers served as an instructor pilot and mission commander in the T-38 ADAIR and F-22 Raptor, leading multinational and multiservice missions worldwide. She has more than 1,400 total flight hours, including more than 200 in combat. Follow @astro_ayers on X and @astro_ayers on Instagram.
With 113 days in space, this mission also will mark Onishi’s second trip to the space station. After being selected as an astronaut by JAXA in 2009, he flew as a flight engineer for Expeditions 48 and 49, becoming the first Japanese astronaut to robotically capture the Cygnus spacecraft. He also constructed a new experimental environment aboard Kibo, the station’s Japanese experiment module. After his first spaceflight, Onishi became certified as a JAXA flight director, leading the team responsible for operating Kibo from JAXA Mission Control in Tsukuba, Japan. He holds a bachelor’s degree in Aeronautics and Astronautics from the University of Tokyo, and was a pilot for All Nippon Airways, flying more than 3,700 flight hours in the Boeing 767. Follow astro_onishi on X.
The Crew-10 mission will also be Peskov’s first spaceflight. Before his selection as a cosmonaut in 2018, he earned a degree in Engineering from the Ulyanovsk Civil Aviation School and was a co-pilot on the Boeing 757 and 767 aircraft for airlines Nordwind and Ikar. Assigned as a test cosmonaut in 2020, he has additional experience in skydiving, zero-gravity training, scuba diving, and wilderness survival.
Learn more about how NASA innovates for the benefit of humanity through NASA’s Commercial Crew Program at:
https://www.nasa.gov/commercialcrew
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Joshua Finch / Jimi Russell
Headquarters, Washington
202-358-1100
joshua.a.finch@nasa.gov / james.j.russell@nasa.gov
Kenna Pell / Sandra Jones
Johnson Space Center, Houston
281-483-5111
kenna.m.pell@nasa.gov / sandra.p.jones@nasa.gov
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Last Updated Feb 18, 2025 LocationNASA Headquarters Related Terms
Humans in Space Anne C. McClain Astronauts Commercial Crew International Space Station (ISS) ISS Research Johnson Space Center Jonny Kim Nichole Ayers View the full article
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By NASA
October 1, 2022 – September 30, 2023
This eighth annual report provides an overall highlight of research results published from October 1, 2022 to September 30, 2023 from investigations operated on the space station. Annual Highlights of Results from the International Space Station (October 1, 2022 – September 30, 2023) (PDF, 19.6 MB).
List of Archived ISS Publications October 1, 2022 – September 30, 2023. (PDF, 1.2 MB)
October 1, 2021 – September 30, 2022
This seventh annual report provides an overall highlight of research results published from October 1, 2021 to September 30, 2022 from investigations operated on the space station. Annual Highlights of Results from the International Space Station (October 1, 2021 – September 30, 2022) (PDF, 7.0 MB).
List of Archived ISS Publications October 1, 2021 – September 30, 2022. (PDF, 1.2 MB)
October 1, 2020 – October 1, 2021
This sixth annual report provides an overall highlight of research results published from October 1, 2020 to October 1, 2021 from investigations operated on the space station. Annual Highlights of Results from the International Space Station (October 1, 2020 – October 1, 2021) (PDF, 7.0 MB)
October 1, 2019 – October 1, 2020
This fifth annual report provides an overall highlight of research results published from October 1, 2019 to October 1, 2020 from investigations operated on the space station. Annual Highlights of Results from the International Space Station (October 1, 2019 – October 1, 2020) (PDF, 7.0 MB)
October 1, 2018 – October 1, 2019
This fourth annual report provides an overall highlight of research results published from October 1, 2018 to October 1, 2019 from investigations operated on the space station. Annual Highlights of Results from the International Space Station (October 1, 2018 – October 1, 2019) (PDF, 3.0 MB)
October 1, 2017 – October 1, 2018
This third annual report provides an overall highlight of research results published from October 1, 2017 to October 1, 2018 from investigations operated on the space station. Annual Highlights of Results from the International Space Station (October 1, 2017 – October 1, 2018) (PDF, 5.8MB)
October 1, 2016 – October 1, 2017
This second annual report provides an overall highlight of research results published from October 1, 2016 to October 1, 2017 from investigations operated on the space station. Annual Highlights of Results from the International Space Station (October 1, 2016 – October 1, 2017) (PDF, 5MB)
October 1, 2015 – October 1, 2016
This first annual report provides an overall highlight of research results published from October 1, 2015 to October 1, 2016 from investigations operated on the space station. Annual Highlights of Results from the International Space Station (October 1, 2015 – October 1, 2016) (PDF, 2.6MB)
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By NASA
The 2024 Annual Highlights of Results from the International Space Station is now available. This new edition contains updated bibliometric analyses, a list of all the publications documented in fiscal year 2024, and synopses of the most recent and recognized scientific findings from investigations conducted on the space station. These investigations are sponsored by NASA and all international partners – CSA (Canadian Space Agency), ESA (European Space Agency), JAXA (Japan Aerospace Exploration Agency), and the State Space Corporation Roscosmos (Roscosmos) – for the advancement of science, technology, and education.
Dr. Dmitry Oleynikov remotely operates a surgical robot aboard the Space Station using controls at the Virtual Incision offices in Lincoln, Nebraska. Robotic Surgery Tech Demo tests techniques for performing a simulated surgical procedure in microgravity using a miniature surgical robot that can be remotely controlled from Earth. Credits: University of Nebraska-Lincoln Between Oct. 1, 2023, and Sept. 30, 2024, more than 350 publications were reported. With approximately 40% of the research produced in collaboration between more than two countries and almost 80% of the high-impact studies published in the past seven years, station has continued to generate compelling and influential science above national and global standards since 2010.
The results achieved from station research provide insights that advance the commercialization of space and benefit humankind.
Some of the findings presented in this edition include:
Improved machine learning algorithms to detect space debris (Italian Space Agency, Roscosmos, ESA) Visuospatial processing before and after spaceflight (CSA) Metabolic changes during fasting intervals in astronauts (ESA) Vapor bubble production for the improvement of thermal systems (NASA) Immobilization of particles for the development of optical materials (JAXA) Maintained function of cardiac 3D stem cells after weeks of exposure to space (NASA) The content in the Annual Highlights of Results from the International Space Station has been reviewed and approved by the International Space Station Program Science Forum, a team of scientists and administrators representing NASA and international partners that are dedicated to planning, improving, and communicating the research operated on the space station.
[See the list of Station Research Results publications here and find the current edition of the Annual Highlights of Results here.]
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By Space Force
The U.S. Space Force made a strong showing at the Daytona 500 to recruit the next generation of service members on February 16, 2025.
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