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Pioneering NASA Astronaut Health Tech Thwarts Heart Failure


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Preparations for Next Moonwalk Simulations Underway (and Underwater)

Image of two engineers wearing white lab coats facing left. The engineer on the right is working on a computer, and the engineer on the left is looking through a microscope.
Dr. Rainee Simons (right) and Dr. Félix Miranda work together to create technology supporting heart health at NASA’s Glenn Research Center in Cleveland.
Credit: NASA

Prioritizing health is important on Earth, and it’s even more important in space. Exploring beyond the Earth’s surface exposes humans to conditions that can impact blood pressure, bone density, immune health, and much more. With this in mind, two NASA inventors joined forces 20 years ago to create a way to someday monitor astronaut heart health on long-duration spaceflight missions. This technology is now being used to monitor the health of patients with heart failure on Earth through a commercial product that is slated to launch in late 2024.

NASA inventors Dr. Rainee Simons, senior microwave communications engineer, and Dr. Félix Miranda, deputy chief of the Communications and Intelligent Systems Division, applied their expertise in radio frequency integrated circuits and antennas to create a miniature implantable sensor system to keep track of astronaut health in space. The technology, which was created at NASA’s Glenn Research Center in Cleveland with seed funds from the agency’s Technology Transfer Office, consists of a small bio-implanted sensor that can transmit a person’s health status from a sensor to a handheld device. The sensor is battery-less and wireless.

“You’re able to insert the sensor and bring it up to the heart or the aorta like a stent – the same process as in a stent implant,” Simons said. “No major surgery is needed for implantation, and operating the external handheld device, by the patient, is simple and easy.”

After Glenn patented the invention, Dr. Anthony Nunez, a heart surgeon, and Harry Rowland, a mechanical engineer, licensed the technology and founded a digital health medical technology company in 2007 called Endotronix, now an Edwards Lifesciences company. The company focuses on enabling proactive heart failure management with data-driven patient-to-physician solutions that detect dangers, based on the Glenn technology. The Endotronix primary monitoring system is called the Cordella Pulmonary Artery (PA) Sensor System. Dr. Nunez became aware of the technology while reading a technical journal that featured the concept, and he saw parallels that could be used in the medical technology industry.

The concept has proven to be an aid for heart failure management through several clinical trials, and patients have experienced improvements in their quality of life. Based on the outcome of Endotronix’s clinical testing to demonstrate safety and effectiveness, in June 2024 the U.S. Food and Drug Administration granted premarket approval to the Cordella PA Sensor System. The system is meant to help clinicians remotely assess, treat, and manage heart failure in patients at home with the goal of reducing hospitalizations.

“If you look at the statistics of how many people have congestive heart failure, high blood pressure… it’s a lot of people,” Miranda said. “To have the medical community saying we have a device that started from NASA’s intellectual property – and it could help people worldwide to be healthy, to enjoy life, to go about their business – is highly gratifying, and it’s very consistent with NASA’s mission to do work for the benefit of all.”

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      -end-
      Alise Fisher
      Headquarters, Washington
      202-358-2546
      alise.m.fisher@nasa.gov
      Natalia Riusech / Nilufar Ramji    
      Johnson Space Center, Houston
      281-483-5111
      natalia.s.riusech@nasa.gov / nilufar.ramji@nasa.gov
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      Last Updated Dec 18, 2024 LocationNASA Headquarters Related Terms
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      Preparations for Next Moonwalk Simulations Underway (and Underwater)
      LISTER (Lunar Instrumentation for Subsurface Thermal Exploration with Rapidity) is one of 10 payloads flying aboard the next delivery for NASA’s CLPS (Commercial Lunar Payload Services) initiative. The instrument is equipped with a drilling system and thermal probe designed to dig into the lunar surface. Photo courtesy: Firefly Aerospace Earth’s nearest neighboring body in the solar system is its Moon, yet to date humans have physically explored just 5% of its surface. It wasn’t until 2023 – building on Apollo-era data and more detailed studies made in 2011-2012 by NASA’s automated GRAIL (Gravity Recovery and Interior Laboratory) mission – that researchers conclusively determined that the Moon has a liquid outer core surrounding a solid inner core.
      As NASA and its industry partners plan for continued exploration of the Moon under Artemis in preparation for future long-duration missions to Mars, improving our understanding of Earth’s 4.5-billion-year-old Moon will help teams of researchers and astronauts find the safest ways to study and live and work on the lunar surface.
      That improved understanding is  the primary goal of a state-of-the-art science instrument called LISTER (Lunar Instrumentation for Subsurface Thermal Exploration with Rapidity), one of 10 NASA payloads flying aboard the next delivery for the agency’s CLPS (Commercial Lunar Payload Services) initiative and set to be carried to the surface by Firefly Aerospace’s Blue Ghost 1 lunar lander.
      Developed jointly by Texas Tech University in Lubbock and Honeybee Robotics of Altadena, California, LISTER will measure the flow of heat from the Moon’s interior. Its sophisticated pneumatic drill will penetrate to a depth of three meters into the dusty lunar regolith. Every half-meter it descends, the drilling system will pause and extend a custom-built thermal probe into the lunar regolith. LISTER will measure two different aspects of heat flow: thermal gradient, or the changes in temperature at various depths, and thermal conductivity, or the subsurface material’s ability to let heat pass through it.
      “By making similar measurements at multiple locations on the lunar surface, we can reconstruct the thermal evolution of the Moon,” said Dr. Seiichi Nagihara, principal investigator for the mission and a geophysics professor at Texas Tech. “That will permit scientists to retrace the geological processes that shaped the Moon from its start as a ball of molten rock, which gradually cooled off by releasing its internal heat into space.”
      Demonstrating the drill’s effectiveness could lead to more innovative drilling capabilities, enabling future exploration of the Moon, Mars, and other celestial bodies.. The science collected by LISTER aims to contribute to our knowledge of lunar geology, improving our ability to establish a long-term presence on the Moon under the Artemis campaign.
      Under the CLPS model, NASA is investing in commercial delivery services to the Moon to enable industry growth and support long-term lunar exploration. As a primary customer for CLPS deliveries, NASA aims to be one of many customers on future flights. NASA’s Marshall Space Flight Center in Huntsville, Alabama, manages the development of seven of the 10 CLPS payloads carried on Firefly’s Blue Ghost lunar lander.
      Learn more about CLPS and Artemis at:
      https://www.nasa.gov/clps
      Alise Fisher
      Headquarters, Washington
      202-358-2546
      Alise.m.fisher@nasa.gov
      Corinne Beckinger 
      Marshall Space Flight Center, Huntsville, Ala. 
      256-544-0034  
      corinne.m.beckinger@nasa.gov 
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      Last Updated Dec 18, 2024 EditorBeth RidgewayContactCorinne M. Beckingercorinne.m.beckinger@nasa.govLocationMarshall Space Flight Center Related Terms
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    • By NASA
      4 min read
      Preparations for Next Moonwalk Simulations Underway (and Underwater)
      From left to right: Astrolab’s FLEX, Intuitive Machines’ Moon RACER, and Lunar Outpost’s Eagle lunar terrain vehicle at NASA’s Johnson Space Center. NASA/Bill Stafford Through NASA’s Artemis campaign, astronauts will land on the lunar surface and use a new generation of spacesuits and rovers as they live, work, and conduct science in the Moon’s South Pole region, exploring more of the lunar surface than ever before. Recently, the agency completed the first round of testing on three commercially owned and developed LTVs (Lunar Terrain Vehicle) from Intuitive Machines, Lunar Outpost, and Venturi Astrolab at NASA’s Johnson Space Center in Houston.
      As part of an ongoing year-long feasibility study, each company delivered a static mockup of their vehicle to Johnson at the end of September, initiated rover testing in October and completed the first round of testing in December inside the Active Response Gravity Offload System (ARGOS) test facility. Lunar surface gravity is one-sixth of what we experience here on Earth, so to mimic this, ARGOS offers an analog environment that can offload pressurized suited subjects for various reduced gravity simulations. 
      NASA astronauts Raja Chari (left) and Randy Bresnik (right) sit inside Lunar Outpost’s Eagle lunar terrain vehicle evaluating the seat configuration during testing at NASA’s Johnson Space Center. NASA/David DeHoyos NASA astronaut Jessica Meir grabs a lunar geology tool from a tool rack on Lunar Outpost’s Eagle lunar terrain vehicle during testing at NASA’s Johnson Space Center.NASA/James Blair NASA astronaut Joe Acaba prepares to climb on top of Intuitive Machines’ Moon RACER lunar terrain vehicle to get to a science payload during testing at NASA’s Johnson Space Center.NASA/Josh Valcarcel NASA astronaut Jessica Meir puts a science sample inside of a storage box on Intuitive Machines’ Moon RACER lunar terrain vehicle during testing at NASA’s Johnson Space Center.NASA/James Blair NASA astronaut Frank Rubio (left) and NASA spacesuit engineer Zach Tejral (right) sit inside Astrolab’s FLEX lunar terrain vehicle evaluating the display interfaces during testing at NASA’s Johnson Space Center.NASA/James Blair NASA astronaut Jessica Watkins stores science payloads on Astrolab’s FLEX lunar terrain vehicle during testing at NASA’s Johnson Space Center.NASA/Robert Markowitz This is the first major test milestone within the Lunar Terrain Vehicle Services contract and to have actual rovers delivered only four months after these companies were awarded is remarkable.
      steve munday
      NASA's Lunar Terrain Vehicle Project Manager
      NASA’s engineering teams conducted tests where suited NASA astronauts and engineers performed tasks, maneuvers, and emergency drills on each rover. With astronauts acting as the test subjects, these human-in-the-loop tests are invaluable as crewmembers provide critical feedback on each rover’s design functionality, evaluate display interfaces and controls, and help identify potential safety concerns or design issues. This feedback is shared directly with each commercial provider, to incorporate changes based on lessons learned as they evolve their rover design.
      “We are excited to have mockups from all three LTV commercial providers here at Johnson Space Center,” said Steve Munday, LTV project manager. “This is the first major test milestone within the Lunar Terrain Vehicle Services contract and to have actual rovers delivered only four months after these companies were awarded is remarkable.” 
      NASA engineer Dave Coan (left) and NASA astronaut Jessica Watkins (right) sit inside from Intuitive Machines’ Moon RACER lunar terrain vehicle evaluating the crew compartment during testing at NASA’s Johnson Space Center.NASA/James Blair Testing consisted of NASA astronauts and engineers taking turns wearing both NASA’s Exploration Extravehicular Mobility Unit planetary prototype spacesuit as well as Axiom Space’s Axiom Extravehicular Mobility Unit lunar spacesuit. The test teams performed evaluations to understand the interactions between the crew, the spacesuits, and the LTV mockups. 
      While wearing NASA’s prototype spacesuit, crew members were suspended from ARGOS allowing teams to mimic theone-sixth gravitational field of the lunar surface. This allowed the crew members to conduct tasks on the outside of each rover, such as gathering or storing lunar geology tools, deploying science payloads, and handling cargo equipment, as if they are walking on the Moon.
      NASA astronaut Joe Acaba raises the solar array panel on Lunar Outpost’s Eagle lunar terrain vehicle during testing at NASA’s Johnson Space Center.NASA/Robert Markowitz While wearing Axiom Space’s pressurized spacesuit, teams evaluated the level of ease or difficulty in mobility crewmembers experienced when entering and exiting the rovers, the crew compartment and design, and the functionality of interacting with display interfaces and hand controls while wearing thick spacesuit gloves.
      As part of testing, teams also conducted emergency drills, where engineers simulated rescuing an incapacitated crew member. As part of NASA’s requirements, each rover must have a design in place that enables an astronaut to single-handedly rescue their crewmates in the event of an emergency.
      NASA astronaut Jessica Watkins picks up a lunar geology tool from a stowage drawer on Astrolab’s FLEX lunar terrain vehicle during testing at NASA’s Johnson Space Center.NASA/Robert Markowitz Since NASA selected the companies, Intuitive Machines, Lunar Outpost, and Venturi Astrolab have been working to meet NASA’s requirements through the preliminary design review. In 2025, the agency plans to issue a request for task order proposals to any eligible providers for a demonstration mission to continue developing the LTV, deliver it to the surface of the Moon, and validate its performance and safety ahead of Artemis V, when NASA intends to begin using the LTV for crewed operations.
      Through Artemis, NASA will send astronauts – including the next Americans, and the first international partner astronaut – to explore the Moon for scientific discovery, technology evolution, economic benefits, and to build the foundation for future crewed missions to Mars. 
      Learn about the rovers, suits, and tools that will help Artemis astronauts to explore more of the Moon: 
      https://go.nasa.gov/3MnEfrB
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      Last Updated Dec 17, 2024 Related Terms
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