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By NASA
CSA (Canadian Space Agency) astronaut Jeremy Hansen, alongside NASA astronauts Victor Glover, Reid Wiseman, and Christina Koch, will launch on the Artemis II mission early next year. The crew will participate in human research studies to provide insights about how the body performs in deep space as part of this mission. Credit: (NASA/James Blair) A sweeping collection of astronaut health studies planned for NASA’s Artemis II mission around the Moon will soon provide agency researchers with a glimpse into how deep space travel influences the human body, mind, and behavior.
During an approximately 10-day mission set to launch in 2026, NASA astronauts Reid Wiseman, Victor Glover, and Christina Koch, and CSA (Canadian Space Agency) astronaut Jeremy Hansen will collect and store their saliva, don wrist monitors that track movement and sleep, and offer other essential data for NASA’s Human Research Program and other agency science teams.
“The findings are expected to provide vital insights for future missions to destinations beyond low Earth orbit, including Mars,” said Laurie Abadie, an aerospace engineer for the program at NASA’s Johnson Space Center in Houston, who strategizes about how to carry out studies on Artemis missions. “The lessons we learn from this crew will help us to more safely accomplish deep space missions and research,” she said.
One study on the Artemis II mission, titled Immune Biomarkers, will explore how the immune system reacts to spaceflight. Another study, ARCHeR (Artemis Research for Crew Health and Readiness), will evaluate how crew members perform individually and as a team throughout the mission, including how easily they can move around within the confined space of their Orion spacecraft. Astronauts also will collect a standardized set of measurements spanning multiple physiological systems to provide a comprehensive snapshot of how spaceflight affects the human body as part of a third study called Artemis II Standard Measures. What’s more, radiation sensors placed inside the Orion capsule cells will collect additional information about radiation shielding functionality and organ-on-a-chip devices containing astronaut cells will study how deep space travel affects humans at a cellular level.
“Artemis missions present unique opportunities, and challenges, for scientific research,” said Steven Platts, chief scientist for human research at NASA Johnson.
Platts explained the mission will need to protect against challenges including exposure to higher radiation levels than on the International Space Station, since the crew will be farther from Earth.
“Together, these studies will allow scientists to better understand how the immune system performs in deep space, teach us more about astronauts’ overall well-being ahead of a Mars mission, and help scientists develop ways to ensure the health and success of crew members,” he said.
Another challenge is the relatively small quarters. The habitable volume inside Orion is about the size of a studio apartment, whereas the space station is larger than a six-bedroom house with six sleeping quarters, two bathrooms, a gym, and a 360-degree view bay window. That limitation affects everything from exercise equipment selection to how to store saliva samples.
Previous research has shown that spaceflight missions can weaken the immune system, reactivate dormant viruses in astronauts, and put the health of the crew at risk. Saliva samples from space-based missions have enabled scientists to assess various viruses, hormones, and proteins that reveal how well the immune system works throughout the mission.
But refrigeration to store such samples will not be an option on this mission due to limited space. Instead, for the Immune Biomarkers study, crew members will supply liquid saliva on Earth and dry saliva samples in space and on Earth to assess changes over time. The dry sample process involves blotting saliva onto special paper that’s stored in pocket-sized booklets.
“We store the samples in dry conditions before rehydrating and reconstituting them,” said Brian Crucian, an immunologist with NASA Johnson who’s leading the study. After landing, those samples will be analyzed by agency researchers.
For the ARCHeR study, participating crew members will wear movement and sleep monitors, called actigraphy devices, before, during, and after the mission. The monitors will enable crew members and flight controllers in mission control to study real-time health and behavioral information for crew safety, and help scientists study how crew members’ sleep and activity patterns affect overall health and performance. Other data related to cognition, behavior, and team dynamics will also be gathered before and after the mission.
“Artemis missions will be the farthest NASA astronauts have ventured into space since the Apollo era,” said Suzanne Bell, a NASA psychologist based at Johnson who is leading the investigation. “The study will help clarify key mission challenges, how astronauts work as a team and with mission control, and the usability of the new space vehicle system.”
Another human research study, Artemis II Standard Measures, will involve collecting survey and biological data before, during, and after the Artemis II mission, though blood collection will only occur before and after the mission. Collecting dry saliva samples, conducting psychological assessments, and testing head, eye, and body movements will also be part of the work. In addition, tasks will include exiting a capsule and conducting simulated moonwalk activities in a pressurized spacesuit shortly after return to Earth to investigate how quickly astronauts recover their sense of balance following a mission.
Crew members will provide data for these Artemis II health studies beginning about six months before the mission and extending for about a month after they return to Earth.
NASA also plans to use the Artemis II mission to help scientists characterize the radiation environment in deep space. Several CubeSats, shoe-box sized satellites that will be deployed into high-Earth orbit during Orion’s transit to the Moon, will probe the near-Earth and deep space radiation environment. Data gathered by these CubeSats will help scientists understand how best to shield crew and equipment from harmful space radiation at various distances from Earth.
Crew members will also keep dosimeters in their pockets that measure radiation exposure in real time. Two additional radiation-sensing technologies will also be affixed to the inside of the Orion spacecraft. One type of device will monitor the radiation environment at different shielding locations and alert crew if they need to seek shelter, such as during a solar storm. A separate collection of four radiation monitors, enabled through a partnership with the German Space Agency DLR, will be placed at various points around the cabin by the crew after launch to gather further information.
Other technologies also positioned inside the spacecraft will gather information about the potential biological effects of the deep space radiation environment. These will include devices called organ chips that house human cells derived from the Artemis II astronauts, through a project called AVATAR (A Virtual Astronaut Tissue Analog Response). After the Artemis II lands, scientists will analyze how these organ chips responded to deep space radiation and microgravity on a cellular level.
Together, the insights from all the human research science collected through this mission will help keep future crews safe as humanity extends missions to the Moon and ventures onward to Mars.
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NASA’s Human Research Program
NASA’s Human Research Program pursues methods and technologies to support safe, productive human space travel. Through science conducted in laboratories, ground-based analogs, commercial missions, the International Space Station and Artemis missions, the program scrutinizes how spaceflight affects human bodies and behaviors. Such research drives the program’s quest to innovate ways that keep astronauts healthy and mission ready as human space exploration expands to the Moon, Mars, and beyond.
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By NASA
3 min read
Preparations for Next Moonwalk Simulations Underway (and Underwater)
NASA’s Langley Research Center Acting Director Dr. Trina Marsh Dyal and Dr. Jeremy Ernst, vice president for Research and Doctoral Programs at Embry-Riddle Aeronautical University, complete the signing of a Space Act Agreement during a ceremony held at NASA Langley in Hampton, Virginia on Thursday, Sept. 11, 2025NASA/Mark Knopp As NASA inspires the world through discovery in a new era of innovation and exploration, NASA’s Langley Research Center in Hampton, Virginia, and Embry-Riddle Aeronautical University are working together to advance research, educational opportunities, and workforce development to enable the next generation of aerospace breakthroughs.
The collaborative work will happen through a Space Act Agreement NASA Langley and Embry-Riddle signed during a ceremony held Thursday at NASA Langley. The agreement will leverage NASA Langley’s aerospace expertise and Embry-Riddle’s specialized educational programs and research to drive innovation in aerospace, research, education, and technology, while simultaneously developing a highly skilled workforce for the future of space exploration and advanced air mobility.
Dr. Trina Marsh Dyal, NASA Langley’s acting center director, and Dr. Jeremy Ernst, vice president for Research and Doctoral Programs at Embry-Riddle, presided over the ceremony.
“NASA Langley values opportunities to partner with colleges and universities on research and technology demonstrations that lay the foundation for tomorrow’s innovations,” said Dyal. “These collaborations play an essential role in advancing aeronautics, space exploration, and science initiatives that benefit NASA, industry, academia, and the nation.”
In addition to forging a formal partnership between NASA Langley and Embry-Riddle, the agreement lays the framework to support Embry-Riddle’s development of an Augmented Reality tool by using NASA sensor technology and data. Augmented Reality uses computer-generated elements to enhance a user’s real-world environment and can help users better visualize data. Incorporating model and lunar landing data from Navigation Doppler Lidar, a technology developed at NASA Langley, this tool will enhance visualization and training for entry, descent, and landing, and deorbit, descent, and landing systems — advancing our capabilities for future Moon and Mars missions.
NASA’s Langley Research Center Acting Director Dr. Trina Marsh Dyal and Dr. Jeremy Ernst, vice president for Research and Doctoral Programs at Embry-Riddle Aeronautical University, sign a Space Act Agreement during a ceremony held at NASA Langley in Hampton, Virginia on Thursday, Sept. 11, 2025.NASA/Mark Knopp “As we work to push the boundaries of what is possible and solve the complexities of a sustained human presence on the lunar surface and Mars, this partnership with Embry-Riddle will not only support NASA’s exploration goals but will also ensure the future workforce is equipped to maintain our nation’s aerospace leadership,” Dyal said.
Embry-Riddle educates more than 30,000 students through its residential campuses in Daytona Beach, Florida, and Prescott, Arizona, and through online programs offered by its
Worldwide Campus, which counts more than 100 locations across the globe, including a site at Naval Station Norfolk in Virginia.
“We are thrilled that this partnership with NASA Langley is making it possible for our faculty, students, and staff to engage with NASA talent and collaborate on cutting-edge aerospace applications and technology,” said Ernst. “This partnership also presents an incredible opportunity for our students to augment direct research experiences, enhancing career readiness as they prepare to take on the aerospace challenges of tomorrow.”
NASA is committed to partnering with a wide variety of domestic and international partners, in academia, industry, and across the government, to successfully accomplish its diverse missions, including NASA’s Artemis campaign which will return astronauts to the Moon and help pave the way for future human missions to Mars.
For more information on programs at NASA Langley, visit:
https://nasa.gov/langley
Brittny McGraw
NASA Langley Research Center
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Last Updated Sep 11, 2025 Related Terms
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4 min read NASA Glenn Tests Mini-X-Ray Technology to Advance Space Health Care
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By NASA
4 min read
Preparations for Next Moonwalk Simulations Underway (and Underwater)
Researchers Kelly Gilkey, Cy Peverill, Daniel Phan, Chase Haddix, and Ariel Tokarz test portable, handheld X-ray systems for use during future long-duration space missions at NASA’s Glenn Research Center in Cleveland on Friday, March 21, 2025. Credit: NASA/Sara Lowthian-Hanna As NASA plans future human exploration missions to the Moon, Mars, and beyond, new and unique challenges emerge — like communication delays and limited return-to-Earth options — so enhanced medical care capabilities are critical. Crews will need non-invasive imaging technology to diagnose medical conditions, like broken bones or dental injuries.
Scientists at NASA’s Glenn Research Center in Cleveland are testing portable, handheld X-ray systems for use during future extended space missions. Having portable X-ray capabilities aboard spacecraft would allow astronauts to immediately assess and treat potential injuries or identify equipment issues without having to disassemble the gear.
“Technological innovations like that of the mini-X-ray will help keep our astronauts healthy as we endeavor farther into space than ever before,” said acting NASA Administrator Sean Duffy. “Future missions to the Moon and Mars will be safer due to the research of our scientists at NASA Glenn.”
NASA reviewed more than 200 commercial systems — analyzing size, weight, image quality, ease-of-use, cost, and safety — and selected three systems for further testing: MinXray, Remedi, and Fujifilm.
“We’re working to provide evidence on why a mini-X-ray system should be included in future space exploration,” said Dr. Chase Haddix, a senior biomedical engineering research contractor working for Universities Space Research Association at NASA Glenn. “These X-rays could be used to detect both clinical and non-clinical diagnostics, meaning they can check an astronaut’s body or identify the location of a tear in an astronaut suit.”
Researchers capture X-ray images of a shape memory alloy rover tire at NASA’s Glenn Research Center in Cleveland on Friday, March 21, 2025. Credit: NASA/Sara Lowthian-Hanna NASA Glenn is collaborating with other centers, including NASA’s Johnson Space Center in Houston and NASA’s Langley Research Center in Hampton, Virginia, and radiography experts at University Hospitals and Cuyahoga Community College in Cleveland.
“We’re fortunate to have enthusiastic medical and radiography experts right here in our community,” said Dr. Cy Peverill, project task lead at NASA Glenn. “Their knowledge and experience are invaluable as we work to test medical technologies that could significantly improve management of astronaut health on future missions to the Moon or Mars.”
Cuyahoga Community College contributed anatomical phantoms, which are lifelike models of the human body, in its radiography laboratory on the Western Campus and dental hygiene clinical facility at the Metropolitan Campus. Faculty and students consulted with NASA researchers on essential imaging principles, including patient positioning, image acquisition, and image quality.
University Hospitals is partnering with NASA Glenn on a medical study with real patients to compare the performance of the X-ray systems against hospital-grade equipment, focusing on usability, image clarity, and diagnostic accuracy.
“Astronauts live and work in small quarters, much smaller spaces than in a hospital,” Haddix said. “The system must be easy to use since astronauts may not be experienced in radiography. The data from these tests will guide the selection of the most suitable system for future missions.”
Researchers capture X-ray images of an astronaut spacesuit at NASA’s Glenn Research Center in Cleveland on Friday, March 21, 2025. Credit: NASA/Sara Lowthian-Hanna Using portable X-rays to improve health care in inaccessible areas is not new, with systems deployed to diagnose medical issues in places such as base camps in Nepal and remote villages in South Africa. NASA researchers theorize that if these systems are successful in high elevations and extreme temperatures on Earth, perhaps they are durable enough for space missions.
Glenn researchers will continue to collect data from all collaborators, including from an X-ray system sourced by SpaceX that launched in April during the Fram2 mission. The crew captured the first human X-ray images in space during their four-day mission to low Earth orbit. NASA plans to select a device near the end of 2025 and will test the chosen system aboard the International Space Station in 2026 or early 2027.
The Mars Campaign Office at NASA Headquarters in Washington and the agency’s Human Research Program at NASA Johnson fund this work as both organizations focus on pursuing technologies and methods to support safe, productive human space travel.
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Explore This Section Science Goddard Space Flight Center Linking Satellite Data and… Overview Learning Resources Science Activation Teams SME Map Opportunities More Science Activation Stories Citizen Science 4 min read
Linking Satellite Data and Community Knowledge to Advance Alaskan Snow Science
Seasonal snow plays a significant role in global water and energy cycles, and billions of people worldwide rely on snowmelt for water resources needs, including water supply, hydropower, agriculture, and more. Monitoring snow water equivalent (SWE) is critical for supporting these applications and for mitigating damages caused by snowmelt flooding, avalanches, and other snow-related disasters. However, our ability to measure SWE remains a challenge, particularly in northern latitudes where in situ SWE observations are sparse and satellite observations are impacted by the boreal forest and environmental conditions. Despite limited in situ SWE measurements, local residents in Arctic and sub-Arctic regions provide a vast and valuable body of place-based knowledge and observations that are essential for understanding snowpack behavior in northern regions.
As part of a joint NASA SnowEx, NASA’s Minority University Research and Education Project (MUREP) for American Indian and Alaska Native STEM (Science, Technology, Engineering, & Mathematics) Engagement (MAIANSE), and Global Learning & Observations to Benefit the Environment (GLOBE) Program partnership, a team of scientists including NASA intern Julia White (NASA Goddard Space Flight Center, University of Alaska Fairbanks), Carrie Vuyovich (NASA Goddard Space Flight Center), Alicia Joseph (NASA Goddard Space Flight Center), and Christi Buffington (University of Alaska Fairbanks, GLOBE Implementation Office) is studying snow water equivalent (SWE) across Interior Alaska. This project combines satellite-based interferometric synthetic aperture radar (InSAR) data, primarily from the Sentinel-1 satellite, with ground-based observations from the Snow Telemetry (SNOTEL) network and GLOBE (Global Learning Observations to Benefit the Environment). Together, these data sources help the team investigate how SWE varies across the landscape and how it affects local ecosystems and communities. The team is also preparing for future integration of data from NASA’s upcoming NISAR (NASA ISRO Synthetic Aperture Radar) mission, which is expected to enhance SWE retrieval capabilities.
After a collaborative visit to the classroom of Tammie Kovalenko in November 2024, Delta Junction junior and senior high school students in vocational agriculture (Vo Ag) classes, including members of Future Farmers of America (FFA), began collecting GLOBE data on a snowdrift located just outside their classroom. As the project progressed, students developed their own research questions. One student, Fianna Rooney, took the project even further — presenting research posters at both the GLOBE International Virtual Science Symposium (IVSS) and both the FFA Regional and National Conventions. Her work highlights the growing role of Alaskan youth in science, and how student-led inquiry can enrich both education and research outcomes. (This trip was funded by the NASA Science Activation Program’s Arctic and Earth SIGNs – STEM Integrating GLOBE & NASA – project at the University of Alaska Fairbanks.)
In February 2025, the team collaborated with Delta Junction Junior High and High School students, along with the Delta Junction Trails Association, to conduct a GLOBE Intensive Observation Period (IOP), “Delta Junction Snowdrifts,” to collect Landcover photos, snow depth, and snow water equivalent data. Thanks to aligned interests and research goals at the Alaska Satellite Facility (ASF), the project was further expanded into Spring 2025. Collaborators from ASF and the Alaska Center for Unmanned Aircraft Systems Integration (ACUASI) collected high resolution airborne data over the snowdrift at the Delta Junction Junior and Senior High School. This complementary dataset helped strengthen connections between satellite observations and ground-based student measurements.
This effort, led by a NASA intern, scientists, students, and Alaskan community members, highlights the power of collaboration in advancing science and education. Next steps will include collaboration with Native Alaskan communities near Delta Junction, including the Healy Lake Tribe, whose vast, generational knowledge will be of great value to deepening our understanding of Alaskan snow dynamics.
Learn more about how NASA’s Science Activation program connects NASA science experts, real content, and experiences with community leaders to do science in ways that activate minds and promote deeper understanding of our world and beyond: https://science.nasa.gov/learn/about-science-activation/
Julia White and Delta Junction student following GLOBE protocols for snow depth. Tori Brannan Share
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