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By NASA
The Axiom Mission 4 and Expedition 73 crews join together for a group portrait inside the International Space Station’s Harmony module. In the front row (from left) are Ax-4 crewmates Tibor Kapu, Peggy Whitson, Shubhanshu Shukla, and Sławosz Uznański-Wiśniewski with Expedition 73 crewmates Anne McClain and Takuya Onishi. In the rear are, Expedition 73 crewmates Alexey Zubritskiy, Kirill Peskov, Sergey Ryzhikov, Jonny Kim, and Nichole Ayers.Credit: NASA NASA will provide live coverage of the undocking and departure of the Axiom Mission 4 private astronaut mission from the International Space Station.
The four-member astronaut crew is scheduled to undock from the space-facing port of the station’s Harmony module aboard the SpaceX Dragon spacecraft at approximately 7:05 a.m. EDT Monday, July 14, pending weather, to begin their return to Earth and splashdown off the coast of California.
Coverage of departure operations will begin with hatch closing at 4:30 a.m. on NASA+. Learn how to watch NASA content through a variety of platforms, including social media.
Peggy Whitson, former NASA astronaut and director of human spaceflight at Axiom Space, ISRO (Indian Space Research Organization) astronaut Shubhanshu Shukla, ESA (European Space Agency) project astronaut Sławosz Uznański-Wiśniewski of Poland, and HUNOR (Hungarian to Orbit) astronaut Tibor Kapu of Hungary, will have spent about two weeks in space at the conclusion of their mission.
The Dragon spacecraft will return with more than 580 pounds of cargo, including NASA hardware and data from over 60 experiments conducted throughout the mission.
NASA’s coverage is as follows (all times Eastern and subject to change based on real-time operations):
Monday, July 14
4:30 a.m. – Hatch closing coverage begins on NASA+.
4:55 a.m. – Crew enters spacecraft followed by hatch closing.
6:45 a.m. – Undocking coverage begins on NASA+, Axiom Space, and SpaceX channels.
7:05 a.m. – Undocking
NASA’s coverage ends approximately 30 minutes after undocking when space station joint operations with Axiom Space and SpaceX conclude. Axiom Space will resume coverage of Dragon’s re-entry and splashdown on the company’s website.
A collaboration between NASA and ISRO allowed Axiom Mission 4 to deliver on a commitment highlighted by President Trump and Indian Prime Minister Narendra Modi to send the first ISRO astronaut to the station. The space agencies participated in five joint science investigations and two in-orbit science, technology, engineering, and mathematics demonstrations. NASA and ISRO have a long-standing relationship built on a shared vision to advance scientific knowledge and expand space collaboration.
The private mission also carried the first astronauts from Poland and Hungary to stay aboard the space station.
The International Space Station is a springboard for developing a low Earth orbit economy. NASA’s goal is to achieve a strong economy off the Earth where the agency can purchase services as one of many customers to meet its science and research objectives in microgravity. NASA’s commercial strategy for low Earth orbit provides the government with reliable and safe services at a lower cost, enabling the agency to focus on Artemis missions to the Moon in preparation for Mars while also continuing to use low Earth orbit as a training and proving ground for those deep space missions.
Learn more about NASA’s commercial space strategy at:
https://www.nasa.gov/commercial-space
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Claire O’Shea
Headquarters, Washington
202-358-1100
claire.a.o’shea@nasa.gov
Anna Schneider
Johnson Space Center, Houston
281-483-5111
anna.c.schneider@nasa.gov
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Last Updated Jul 11, 2025 LocationNASA Headquarters Related Terms
International Space Station (ISS) Commercial Crew Commercial Space Commercial Space Programs Humans in Space ISS Research Johnson Space Center Space Operations Mission Directorate View the full article
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By NASA
The crew of NASA’s SpaceX Crew-11 mission sit inside a Dragon training spacecraft at SpaceX in Hawthorne, California. Pictured from left: Roscosmos cosmonaut Oleg Platonov, NASA astronauts Mike Fincke and Zena Cardman, and JAXA (Japan Aerospace Exploration Agency) astronaut Kimiya Yui (Credit: SpaceX). NASA’s SpaceX Crew-11 mission is set to launch a four-person crew to the International Space Station later this summer. Some of the crew have volunteered to participate in a series of experiments to address health challenges astronauts may face on deep space missions during NASA’s Artemis campaign and future human expeditions to Mars.
The research during Crew-11 includes simulated lunar landings, tactics to safeguard vision, and other human physiology studies led by NASA’s Human Research Program.
Select crew members will participate in a series of simulated Moon landings, before, during, and after their flight. Using a handheld controller and multiple screens, the astronauts will fly through simulated scenarios created to resemble the lunar South Pole region that Artemis crews plan to visit. This experiment allows researchers to evaluate how different gravitational forces may disorient astronauts and affect their ability to pilot a spacecraft, like a lunar lander.
“Even though many landing tasks are automated, astronauts must still know how to monitor the controls and know when to take over to ensure a safe landing,” said Scott Wood, a neuroscientist at NASA’s Johnson Space Center in Houston coordinating the scientific investigation. “Our study assesses exactly how changes in gravity affect spatial awareness and piloting skills that are important for navigating these scenarios.”
A ground control group completing the same tasks over a similar timeframe will help scientists better understand gravitational effects on human performance. The experiment’s results could inform the pilot training needed for future Artemis crews.
“Experiencing weightlessness for months and then feeling greater levels of gravity on a planet like Mars, for example, may increase the risk of disorientation,” said Wood. “Our goal is to help astronauts adapt to any gravitational change, whether it’s to the Moon, a new planet, or landing back on Earth.”
Other studies during the mission will explore possible ways to treat or prevent a group of eye and brain changes that can occur during long-duration space travel, called spaceflight associated neuro-ocular syndrome (SANS).
Some researchers suspect the redistribution of bodily fluids in constant weightlessness may increase pressure in the head and contribute to SANS. One study will investigate fluid pressure on the brain while another will examine how the body processes B vitamins and whether supplements can affect how astronauts respond to bodily fluid shifts. Participating crew members will test whether a daily B vitamin supplement can eliminate or ease symptoms of SANS. Specific crew members also will wear thigh cuffs to keep bodily fluids from traveling headward.
Crew members also will complete another set of experiments, called CIPHER (Complement of Integrated Protocols for Human Exploration Research), which measures how multiple systems within the human body change in space. The study includes vision assessments, MRI scans, and other medical exams to provide a complete overview of the whole body’s response to long-duration spaceflight.
Several other studies involving human health and performance are also a part of Crew-11’s science portfolio. Crew members will contribute to a core set of measurements called Spaceflight Standard Measures, which collects physical data and biological samples from astronauts and stores them for other comparative studies. Participants will supply biological samples, such as blood and urine, for a study characterizing how spaceflight alters astronauts’ genetic makeup. In addition, volunteers will test different exercise regimens to help scientists explore what activities remain essential for long-duration journeys.
After landing, participating crew members will complete surveys to track any discomfort, such as scrapes or bruises, acquired from re-entry. The data will help clarify whether mission length increases injury risks and could help NASA design landing systems on future spacecraft as NASA prepares to travel to the Moon, Mars, and beyond.
NASA’s Human Research Program pursues methods and technologies to support safe, productive human space travel. Through science conducted in laboratories, ground-based analogs, and aboard the International Space Station, the program investigates how spaceflight affects human bodies and behaviors. Such research drives NASA’s quest to innovate ways that keep astronauts healthy and mission-ready.
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