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Pioneering Research for Early Prediction of Alzheimer’s and Related Dementias EUREKA Challenge


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The National Institute on Aging (NIA), a component of the National Institutes of Health (NIH) seeks to stimulate the use of data resources with appropriate sample diversity, including data relevant to under-resourced, underserved communities disproportionately burdened by AD/ADRD. For example, for Asian, Black, or Hispanic older adults, the protein amyloid – which has long been considered a biomarker for AD – might have a smaller role in determining cognitive impairment than other factors such as co-occurring chronic medical conditions (hypertension, diabetes) and sociodemographic and systemic factors, each of which has been found to contribute to racial and ethnic disparities in dementia diagnoses (below; Wilkins et al., 2022). This highlights the importance of also identifying novel (non-amyloid, non-tau) biomarkers and non-biological (e.g., social determinants of health) predictors in adults from underrepresented racial and ethnic groups (Dark and Walker, 2022). The goal is to inform novel approaches to early detection that might ultimately lead to more accurate tests, tools, and methodologies for clinical and research purposes.

Government Agency: National Institutes of Health

Award: Phase 1: $200,000; Phase 2: $250,000; Phase 3: $200,000

Open Date: Phase 1: September 2023; Phase 2: September 2024; Phase 3: September 2025

Close date: Phase 1: January 2024; Phase 2: TBD; Phase 3: TBD

For more information, visit: https://www.drivendata.org/competitions/group/nih-nia-alzheimers-adrd-competition/

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      2023 Workshop of Analysis Working Group members, Washington, D.C., November 14, 2023. Now, you are invited to join their quest to understand how life can thrive in deep space! Want to learn more first? Join our live virtual event April 17 at 3pm Eastern Time to hear an overview of the OSDR AWG’s operations. Photo: NASA OSDR Team How can life thrive in deep space? The Open Science Data Repository Analysis Working Groups invite volunteers from all backgrounds to help answer this question. Request to join these citizen science groups to help investigate how life adapts to space environments, exploring topics like radiation effects, microgravity’s impact on human and plant health, and how microbes change in orbit.
      Currently, nine Analysis Working Groups (AWGs) hold monthly meetings to advance their specific focus areas. Participants collaborate using an online platform, the AWG “Forum-Space”, where they connect with peers and experts, join discussions, and contribute to over 20 active projects. 
      The AWGs work with data primarily from the NASA Open Science Data Repository (OSDR), a treasure trove of spaceflight data on physiology, molecular biology, bioimaging, and much more. For newcomers, there are tutorials and a comprehensive paper covering all aspects of the repository and the AWG community. You can explore 500+ studies, an omics multi-study visualization portal, the environmental data app, and RadLab, a portal for radiation telemetry data. (“Omics” refers to fields of biology that end in “omics,” like “genomics”.)   
      Each of the nine AWGs has a Lead who organizes their group and holds monthly virtual meetings. Once you join, make sure to connect with the Lead and get on the agenda so you can introduce yourself. Learn more about the AWGs here.
      Have an idea for a new project? Propose a new project and help lead it! From data analysis and visualization to shaping data standards and conducting literature meta-analyses, there’s a place for everyone to contribute. Request to join, and together, we can address a great challenge for humanity: understanding and enabling life to thrive in deep space! 
      Want to learn more?
      On April 17 at 3pm Eastern Time, the NASA Citizen Science Leaders Series is hosting an virtual event with Ryan Scott about these Analysis Working Groups and their work. Ryan is the Science Lead for the Ames Life Sciences Data Archive and the liaison between the Open Data Science Repository and the Analysis Working Groups. Click here to register for this event!
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      Last Updated Apr 01, 2025 Related Terms
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      Using the unique infrared sensitivity of the NASA/ESA/CSA James Webb Space Telescope, researchers can examine ancient galaxies to probe secrets of the early Universe. Now, an international team of astronomers has identified bright hydrogen emission from a galaxy in an unexpectedly early time in the Universe’s history. The surprise finding is challenging researchers to explain how this light could have pierced the thick fog of neutral hydrogen that filled space at that time.
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