Jump to content

Pioneering Research for Early Prediction of Alzheimer’s and Related Dementias EUREKA Challenge


NASA

Recommended Posts

  • Publishers
Group of people in silhouette with a lightbulb hovering above them to symbolize a great idea coming from a team of solvers.

The National Institute on Aging (NIA), a component of the National Institutes of Health (NIH) seeks to stimulate the use of data resources with appropriate sample diversity, including data relevant to under-resourced, underserved communities disproportionately burdened by AD/ADRD. For example, for Asian, Black, or Hispanic older adults, the protein amyloid – which has long been considered a biomarker for AD – might have a smaller role in determining cognitive impairment than other factors such as co-occurring chronic medical conditions (hypertension, diabetes) and sociodemographic and systemic factors, each of which has been found to contribute to racial and ethnic disparities in dementia diagnoses (below; Wilkins et al., 2022). This highlights the importance of also identifying novel (non-amyloid, non-tau) biomarkers and non-biological (e.g., social determinants of health) predictors in adults from underrepresented racial and ethnic groups (Dark and Walker, 2022). The goal is to inform novel approaches to early detection that might ultimately lead to more accurate tests, tools, and methodologies for clinical and research purposes.

Government Agency: National Institutes of Health

Award: Phase 1: $200,000; Phase 2: $250,000; Phase 3: $200,000

Open Date: Phase 1: September 2023; Phase 2: September 2024; Phase 3: September 2025

Close date: Phase 1: January 2024; Phase 2: TBD; Phase 3: TBD

For more information, visit: https://www.drivendata.org/competitions/group/nih-nia-alzheimers-adrd-competition/

View the full article

Link to comment
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

  • Similar Topics

    • By NASA
      This illustration shows a red, early-universe dwarf galaxy that hosts a rapidly feeding black hole at its center. Using data from NASA’s James Webb Space Telescope and Chandra X-ray Observatory, a team of astronomers have discovered this low-mass supermassive black hole at the center of a galaxy just 1.5 billion years after the Big Bang. It is pulling in matter at a phenomenal rate — over 40 times the theoretical limit. While short lived, this black hole’s “feast” could help astronomers explain how supermassive black holes grew so quickly in the early universe.NOIRLab/NSF/AURA/J. da Silva/M. Zamani A rapidly feeding black hole at the center of a dwarf galaxy in the early universe, shown in this artist’s concept, may hold important clues to the evolution of supermassive black holes in general.
      Using data from NASA’s James Webb Space Telescope and Chandra X-ray Observatory, a team of astronomers discovered this low-mass supermassive black hole just 1.5 billion years after the big bang. The black hole is pulling in matter at a phenomenal rate — over 40 times the theoretical limit. While short lived, this black hole’s “feast” could help astronomers explain how supermassive black holes grew so quickly in the early universe.
      Supermassive black holes exist at the center of most galaxies, and modern telescopes continue to observe them at surprisingly early times in the universe’s evolution. It’s difficult to understand how these black holes were able to grow so big so rapidly. But with the discovery of a low-mass supermassive black hole feasting on material at an extreme rate so soon after the birth of the universe, astronomers now have valuable new insights into the mechanisms of rapidly growing black holes in the early universe.
      The black hole, called LID-568, was hidden among thousands of objects in the Chandra X-ray Observatory’s COSMOS legacy survey, a catalog resulting from some 4.6 million Chandra observations. This population of galaxies is very bright in the X-ray light, but invisible in optical and previous near-infrared observations. By following up with Webb, astronomers could use the observatory’s unique infrared sensitivity to detect these faint counterpart emissions, which led to the discovery of the black hole.
      The speed and size of these outflows led the team to infer that a substantial fraction of the mass growth of LID-568 may have occurred in a single episode of rapid accretion.
      LID-568 appears to be feeding on matter at a rate 40 times its Eddington limit. This limit relates to the maximum amount of light that material surrounding a black hole can emit, as well as how fast it can absorb matter, such that its inward gravitational force and outward pressure generated from the heat of the compressed, infalling matter remain in balance.
      These results provide new insights into the formation of supermassive black holes from smaller black hole “seeds,” which current theories suggest arise either from the death of the universe’s first stars (light seeds) or the direct collapse of gas clouds (heavy seeds). Until now, these theories lacked observational confirmation.
      The new discovery suggests that “a significant portion of mass growth can occur during a single episode of rapid feeding, regardless of whether the black hole originated from a light or heavy seed,” said International Gemini Observatory/NSF NOIRLab astronomer Hyewon Suh, who led the research team.
      A paper describing these results (“A super-Eddington-accreting black hole ~1.5 Gyr after the Big Bang observed with JWST”) appears in the journal Nature Astronomy.
      About the Missions
      NASA’s Marshall Space Flight Center manages the Chandra program. The Smithsonian Astrophysical Observatory’s Chandra X-ray Center controls science operations from Cambridge, Massachusetts, and flight operations from Burlington, Massachusetts.
      The James Webb Space Telescope is the world’s premier space science observatory. Webb is solving mysteries in our solar system, looking beyond to distant worlds around other stars, and probing the mysterious structures and origins of our universe and our place in it. Webb is an international program led by NASA with its partners, ESA (European Space Agency) and CSA (Canadian Space Agency).
      Read more from NASA’s Chandra X-ray Observatory.
      Learn more about the Chandra X-ray Observatory and its mission here:
      https://www.nasa.gov/chandra
      https://chandra.si.edu
      News Media Contact
      Elizabeth Laundau
      NASA Headquarters
      Washington, DC
      202-923-0167
      elizabeth.r.landau@nasa.gov
      Lane Figueroa
      Marshall Space Flight Center, Huntsville, Alabama
      256-544-0034
      lane.e.figueroa@nasa.gov
      View the full article
    • By NASA
      5 Min Read Wearable Tech for Space Station Research
      A wearable monitoring device is visible on the left wrist of NASA astronaut Jeanette Epps. Credits: NASA Science in Space Nov 2024
      Many of us wear devices that count our steps, measure our heart rate, track sleep patterns, and more. This information can help us make healthy decisions – research shows the devices encourage people to move more, for example – and could flag possible problems, such as an irregular heartbeat.
      Wearable monitors also have become common tools for research on human health, including studies on the International Space Station. Astronauts have worn special watches, headbands, vests, and other devices to help scientists examine sleep quality, effectiveness of exercise, heart health, and more.
      Warm to the core
      Spaceflight can affect body temperature regulation and daily rhythms due to factors such as the absence of convection (a natural process that transfers heat away from the body) and changes in the cardiovascular and metabolic systems.
      A current investigation from ESA (European Space Agency), Thermo-Mini or T-Mini examines how the body regulates its core temperature during spaceflight. The study uses a non-invasive headband monitor that astronauts can wear for hours at a time. Data from the monitor allow researchers to determine the effect on body temperature from environmental and physiological factors such as room temperature and humidity, time of day, and physical stress. The same type of sensor already is used on Earth for research in clinical environments, such as improving incubators, and studies of how hotter environments affect human health.
      Thermolab, an earlier ESA investigation, examined thermoregulatory and cardiovascular adaptations during rest and exercise in microgravity. Researchers found that core body temperature rises higher and faster during exercise in space than on Earth and that the increase was sustained during rest, a phenomenon that could affect the health of crew members on long-term spaceflight. The finding also raises questions about the thermoregulatory set point humans are assumed to have as well as our ability to adapt to climate change on Earth.
      NASA astronaut Nick Hague wears the T-mini device while exercising.NASA To sleep, perchance to dream
      Spaceflight is known to disrupt sleep-wake patterns. Actiwatch Spectrum, a device worn on the wrist, contains an accelerometer to measure motion and photodetectors to monitor ambient lighting. It is an upgrade of previous technology used on the space station to monitor the length and quality of crew member sleep. Data from earlier missions show that crew members slept significantly less during spaceflight than before and after. The Actiwatch Sleep-Long investigation used an earlier version of the device to examine how ambient light affects the sleep-wake cycle and found an association between sleep deficiency and changes during spaceflight in circadian patterns, or the body’s response to a normal 24-hour light and dark cycle. Follow up studies are testing lighting systems to address these effects and help astronauts maintain healthy circadian rhythms.
      NASA astronaut Sunita Williams wears an Actiwatch as she conducts research.NASA Wearable Monitoring tested a lightweight vest with embedded sensors to monitor heart rate and breathing patterns during sleep and help determine whether changes in heart activity affect sleep quality. The technology offers a significant advantage by monitoring heart activity without waking the test subject and could help patients on Earth with sleep disorders. Researchers reported positive performance and good quality of recorded signals, suggesting that the vest can contribute to comprehensive monitoring of individual health on future spaceflight and in some settings on Earth as well.
      These and other studies support development of countermeasures to improve sleep for crew members, helping to maintain alertness and lessen fatigue during missions.
      (Not) waiting to exhale
      Humans exhale carbon dioxide and too much of it can build up in closed environments, causing headaches, dizziness, and other symptoms. Spacecraft have systems to remove this substance from cabin air, but pockets of carbon dioxide can form and be difficult to detect and remove. Personal CO2 Monitor tested specially designed sensors attached to clothing to monitor the wearer’s immediate surroundings. Researchers reported that the devices functioned adequately as either crew-worn or static monitors, an important step toward using them to determine how carbon dioxide behaves in enclosed systems like spacecraft.
      One of the wearable carbon dioxide monitors clipped to the wall near a crew sleeping compartment. Radiation in real time
      EVARM, an investigation from CSA (Canadian Space Agency), used small wireless dosimeters carried in a pocket to measure radiation exposure during spacewalks. The data showed that this method is a feasible way to measure radiation exposure, which could help focus routine dosage monitoring where it is most needed. Any shielding and countermeasures developed also could help protect people who work in high-radiation areas on Earth.
      ESA’s Active Dosimeter tested a radiation dosimeter worn by crew members to measure changes in their exposure over time based on the space station’s orbit and altitude, the solar cycle, and solar flares. Measurements from the device allowed researchers to analyze radiation dosage across an entire space mission.
      ESA astronaut Thomas Pesquet holds one of the mobile units for the Active Dosimeter study.NASA The Active Dosimeter also was among the instruments used to measure radiation on NASA’s Orion spacecraft during its 25.5-day uncrewed Artemis I mission around the Moon and back in 2022.
      Another device tested on the space station and then on Artemis I, AstroRad Vest is designed to protect astronauts from solar particle events. Researchers used these and other radiation measuring devices to show that Orion’s design can protect its crew from potentially hazardous radiation levels during lunar missions.
      The International Space Station serves as an important testbed for these technologies and many others being developed for future missions to the Moon and beyond.
      Melissa Gaskill
      International Space Station Research Communications Team
      Johnson Space Center
      Keep Exploring Discover More Topics From NASA
      Humans In Space
      Space Station Technology Demonstration
      Space Station Research and Technology
      Station Science 101: Human Research
      View the full article
    • By NASA
      On Sept. 20, 2024, four students experienced the wonder of space exploration at NASA’s Johnson Space Center in Houston, taking part in an international competition that brought their work to life aboard the International Space Station.  

      Now in its fifth year, the Kibo Robot Programming Challenge (Kibo-RPC) continues to push the boundaries of robotics, bringing together the world’s brightest young minds for a real-world test of programming, problem-solving, and innovation.
      The Kibo Robot Programming Challenge (Kibo-RPC) students tour the Gateway Habitation and Logistics Outpost module at NASA’s Johnson Space Center in Houston.NASA/Helen Arase Vargas The stakes reached new heights in this year’s competition, with 661 teams totaling 2,788 students from 35 countries and regions competing to program robots aboard the orbiting laboratory. Organized by the Japan Aerospace Exploration Agency in collaboration with the United Nations Office for Outer Space Affairs, the challenge provided a unique platform for students to test their skills on a global stage. 

      Meet Team Salcedo 

      Representing the U.S., Team Salcedo is composed of four talented students: Aaron Kantsevoy, Gabriel Ashkenazi, Justin Bonner, and Lucas Paschke. Each member brought a unique skill set and perspective, contributing to the team’s well-rounded approach to the challenge. 
      From left to right are Kibo-RPC students Gabriel Ashkenazi, Lucas Paschke, Aaron Kantsevoy, and Justin Bonner. NASA/Helen Arase Vargas The team was named in honor of Dr. Alvaro Salcedo, a robotics teacher and competitive robotics coach who had a significant impact on Kantsevoy and Bonner during high school. Dr. Salcedo played a crucial role in shaping their interests and aspirations in science, technology, engineering, and mathematics (STEM), inspiring them to pursue careers in these fields. 

      Kantsevoy, a computer science major at Georgia Institute of Technology, or Georgia Tech, led the team with three years of Kibo-RPC experience and a deep interest in robotics and space-based agriculture. Bonner, a second-year student at the University of Miami, is pursuing a triple major in computer science, artificial intelligence, and mathematics. Known for his quick problem-solving, he played a key role as a strategist and computer vision expert. Paschke, a first-time participant and computer science student at Georgia Tech, focused on intelligence systems and architecture, and brought fresh insights to the table. Ashkenazi, also studying computer science at Georgia Tech, specialized in computer vision and DevOps, adding depth to the team’s technical capabilities. 

      AstroBee Takes Flight 

      The 2024 competition tasked students with programming AstroBee, a free-flying robot aboard the station, to navigate a complex course while capturing images scattered across the orbital outpost. For Team Salcedo, the challenge reached its peak as their code was tested live on the space station.  
      The Kibo-RPC students watch their code direct Astrobee’s movements at Johnson Space Center with NASA Program Specialist Jamie Semple on Sept. 20, 2024.NASA/Helen Arase Vargas The robot executed its commands in real time, maneuvering through the designated course to demonstrate precision, speed, and adaptability in the microgravity environment. Watching AstroBee in action aboard the space station offered a rare glimpse of the direct impact of their programming skills and added a layer of excitement that pushed them to fine-tune their approach. 

      Overcoming Challenges in Real Time 

      Navigating AstroBee through the orbital outpost presented a set of unique challenges. The team had to ensure the robot could identify and target images scattered throughout the station with precision while minimizing the time spent between locations.  
      The Kibo-RPC students watch in real time as the free-flying robot Astrobee performs maneuvers aboard the International Space Station, executing tasks based on their input to test its capabilities. NASA/Helen Arase Vargas Using quaternions for smooth rotation in 3D space, they fine-tuned AstroBee’s movements to adjust camera angles and capture images from difficult positions without succumbing to the limitations of gimbal lock. Multithreading allowed the robot to simultaneously process images and move to the next target, optimizing the use of time in the fast-paced environment. 

      The Power of Teamwork and Mentorship 

      Working across different locations and time zones, Team Salcedo established a structured communication system to ensure seamless collaboration. Understanding each team member’s workflow and adjusting expectations accordingly helped them maintain efficiency, even when setbacks occurred. 
      Team Salcedo tour the Space Vehicle Mockup Facility with their NASA mentors (from top left to right) Education Coordinator Kaylie Mims, International Space Station Research Portfolio Manager Jorge Sotomayer, and Kibo-RPC Activity Manager Jamie Semple. NASA/Helen Arase Vargas Mentorship was crucial to their success, with the team crediting several advisors and educators for their guidance. Kantsevoy acknowledged his first STEM mentor, Casey Kleiman, who sparked his passion for robotics in middle school.  

      The team expressed gratitude to their Johnson mentors, including NASA Program Specialist Jamie Semple, Education Coordinator Kaylie Mims, and International Space Station Research Portfolio Manager Jorge Sotomayer, for guiding them through the program’s processes and providing support throughout the competition. 

      They also thanked NASA’s Office of STEM Engagement for offering the opportunity to present their project to Johnson employees.  

      “The challenge mirrors how the NASA workforce collaborates to achieve success in a highly technical environment. Team Salcedo has increased their knowledge and learned skills that they most likely would not have acquired individually,” said Semple. “As with all of our student design challenges, we hope this experience encourages the team to continue their work and studies to hopefully return to NASA in the future as full-time employees.” 

      Pushing the Boundaries of Innovation 

      The Kibo-RPC allowed Team Salcedo to experiment with new techniques, such as Slicing Aided Hyperinference—an approach that divides images into smaller tiles for more detailed analysis. Although this method showed promise in detecting smaller objects, it proved too time-consuming under the competition’s time constraints, teaching the students valuable lessons about prioritizing efficiency in engineering. 
      The Kibo-RPC students present their robotic programming challenge to the International Space Station Program. NASA/Bill Stafford For Team Salcedo, the programming challenge taught them the value of communication, the importance of learning from setbacks, and the rewards of perseverance. The thrill of seeing their code in action on the orbital outpost was a reminder of the limitless possibilities in robotics and space exploration. 

      Inspiring the Next Generation 

      With participants from diverse backgrounds coming together to compete on a global platform, the Kibo-RPC continues to be a proving ground for future innovators.  

      The challenge tested the technical abilities of students and fostered personal growth and collaboration, setting the stage for the next generation of robotics engineers and leaders. 
      The Kibo-RPC students and their mentors at the Mission Control Center. NASA/Helen Arase Vargas
      As Team Salcedo looks ahead, they carry with them the skills, experiences, and inspiration needed to push the boundaries of human space exploration.  

      “With programs like Kibo-RPC, we are nurturing the next generation of explorers – the Artemis Generation,” said Sotomayer. “It’s not far-fetched to imagine that one of these students could eventually be walking on the Moon or Mars.” 

      The winners were announced virtually from Japan on Nov. 9, with Team Salcedo achieving sixth place. 

      Watch the international final round event here. 

      For more information on the Kibo Robot Programming Challenge, visit: https://jaxa.krpc.jp/
      View the full article
    • By NASA
      5 min read
      Preparations for Next Moonwalk Simulations Underway (and Underwater)
      NASA provides a variety of pathways for those outside the agency to contribute to authentic and meaningful research. Whether you’re a student pursuing a degree in STEM (science, technology, engineering, or mathematics), an educator looking for new ways to engage your classroom, or a citizen scientist enthusiastic about sharing your observations, there’s a wide array of opportunities to get involved in NASA research.
      Citizen scientists around the world participate in environmental observation and measurement efforts through GLOBE.NASA Everybody
      People from all around the world can make contributions to NASA research through citizen science projects and other opportunities available to the public.
      Share your observations and take measurements in your part of the world through GLOBE (Global Learning and Observations to Benefit the Environment), an international science and education initiative that engages students, teachers, and the public in collecting and analyzing environmental data. Do you have a relevant idea for human health science research that could be performed on the future Gateway lunar space station? Follow these steps to share your idea for consideration. The Prizes, Challenges, and Crowdsourcing program through NASA’s Space Technology Mission Directorate invites citizen scientists to develop innovations in recycling material waste on deep space missions, develop aids/devices for navigating on the lunar surface during future Artemis missions, and more. Do you have the “right stuff” to participate in a simulated deep space mission? NASA’s HERA (the Human Exploration Research Analog) is seeking healthy subjects to participate in 45-day simulations to study the physiological and psychological effects of isolation and confinement on humans to help prepare for future missions to the Moon and Mars. Visit the NASA Citizen Science webpage for more opportunities to discover the secrets of the universe, search for life elsewhere, and improve life on Earth and in space. This collage features the winning designs in the 2024 Dream with Us Design Challenge, which asks students to dream of innovations for the future of aviation.NASA Middle and High School Students
      Students can gain valuable experience while making a difference in the future of aeronautics and exploration.
      Rising high school juniors and seniors are eligible to apply for the four-week Gene Lab for High School Students training program sponsored by NASA’s Ames Research Center in Silicon Valley, California. The program focuses on collecting and analyzing complex biological data such as genetic codes, and computational biology. Through the annual TechRise Student Challenge offered by NASA’s Space Technology Mission Directorate, U.S. students in grades 6 to 12 form teams and design an experiment to fly on a suborbital flight platform such as a high-altitude balloon. Interested in aviation? The Dream With Us Design Challenge through NASA’s Aeronautics Research Mission Directorate invites students in grades 6 to 12 to envision new innovations that will improve the safety, sustainability, and accessibility of aviation systems and technology. Through NASA internships, U.S. students ages 16 and up can boost their research experience and contribute to NASA’s work with the guidance of an agency mentor. This collage features the winning designs in the 2024 Dream with Us Design Challenge, which asks students to dream of innovations for the future of aviation.NASA Undergraduate and Graduate Students
      NASA offers a variety of research opportunities for college students preparing to launch their own exciting careers in STEM.
      NASA’s Established Program to Stimulate Competitive Research (EPSCoR) grants competitive awards to enable college and university students within specific U.S. jurisdictions to participate in cutting-edge research projects that address NASA’s challenges and needs. The National Space Grant College and Fellowship Project (Space Grant), is a national network of colleges and universities comprising a total of 52 consortia across the U.S. These consortia fund several research opportunities for students attending member colleges and universities. Look up your state’s Space Grant consortium website to discover available opportunities. NASA internships are available in a wide range of opportunities for undergraduate and graduate students, enabling meaningful contributions to NASA’s missions as well as authentic experience as a part of the agency’s world-class workforce. Through the University Student Research Challenge, students are invited to propose their ideas describing innovative new approaches to tackling one of six major research areas as outlined by NASA’s Aeronautics Research Mission Directorate. Students can take part in valuable studies of the ever-changing Earth system through NASA’s Earth Science Division’s Early Career Research (ECR) program. ECR includes the eight-week Student Airborne Research Program, the Climate Change Research Initiative, and more. College students at Minority Serving Institutions can contribute to the agency’s exploration goals through many opportunities offered by NASA’s Minority University Research and Education Project (MUREP). Educators of grades K-8 take part in a workshop hosted by NASA’s Next Gen STEM.NASA Educators
      NASA provides opportunities for educators to participate in authentic aerospace research, as well as to engage their students in research in the classroom.
      Space Grant offers a variety of opportunities for educators, from curriculum enhancement and faculty development to grants enabling teachers to bring NASA research into the classroom. Look up your state’s Space Grant consortium website to discover available opportunities. NASA welcomes interns with professional teaching experience to help foster the education and curiosity of students who will shape the future workforce. Visit NASA Internships to learn more and find current opportunities. Through NASA’s Climate Change Research Initiative, part of the agency’s Earth Science Division’s Early Career Research Program, high school STEM educators can join a research team led by NASA scientists to focus on a research area related to climate change. There’s More to Explore
      Explore available NASA STEM learning experiences, such as internship roles, student competitions, or engagements with NASA researchers, through NASA’s STEM Gateway platform. Visit NASA’s Learning Resources webpage for the latest news and resources from the agency’s Office of STEM Engagement.
      Keep Exploring Discover More STEM Topics From NASA
      NASA STEM Engagement Funding Opportunities
      For Colleges and Universities
      About STEM Engagement at NASA
      NASA EXPRESS Newsletter Sign-up
      View the full article
    • By European Space Agency
      The Space Resources Challenge was launched last week, an opportunity for innovators to pioneer the technologies that will help humankind live and work sustainably on the Moon.
      View the full article
  • Check out these Videos

×
×
  • Create New...