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By NASA
4 Min Read Heart Health
Jessica Meir conducts cardiac research in the space station’s Life Sciences Glovebox. Credits: NASA Science in Space: February 2025
February was first proclaimed as American Heart Month in 1964. Since then, its 28 (or 29) days have served as an opportunity to encourage people to focus on their cardiovascular health.
The International Space Station serves as a platform for a variety of ongoing research on human health, including how different body systems adapt to weightlessness. This research includes assessing cardiovascular health in astronauts during and after spaceflight and other studies using models of the cardiovascular system, such as tissue cultures. The goal of this work is to help promote heart health for humans in space and everyone on Earth. For this Heart Month, here is a look at some of this spaceflight research
Building a better heart model
Media exchange in the tissue chambers for the Engineered Heart Tissue investigation.NASA Microgravity exposure is known to cause changes in cardiovascular function. Engineered Heart Tissues assessed these changes using 3D cultured cardiac tissues that model the behavior of actual heart tissues better than traditional cell cultures. When exposed to weightlessness, these “heart-on-a-chip” cells behaved in a manner similar to aging on Earth. This finding suggests that these engineered tissues can be used to investigate the effects of space radiation and long-duration spaceflight on cardiac function. Engineered tissues also could support development of measures to help protect crew members during a mission to Mars. Advanced 3D culture methodology may inform development of strategies to prevent and treat cardiac diseases on Earth as well.
Private astronaut heart health
In April 2022, the 11-person station crew included (clockwise on the outside from bottom right) NASA astronaut Tom Marshburn; Roscomos cosmonauts Oleg Artemyev, Denis Matveev, and Sergey Korsakov; NASA astronauts Raja Chari, Kayla Barron, and Matthias Maurer; and Ax-1 astronauts (center row from left) Mark Pathy, Eytan Stibbe, Larry Conner, and Michael López-Alegría.-Alegria.NASA For decades, human research in space has focused on professional and government-agency astronauts, but commercial spaceflight opportunities now allow more people to participate in microgravity research. Cardioprotection Ax-1 analyzed cardiovascular and general health in private astronauts on the 17-day Axiom-1 mission.
The study found that 14 health biomarkers related to cardiac, liver, and kidney health remained within normal ranges during the mission, suggesting that spaceflight did not significantly affect the health of the astronaut subjects. This study paves the way for monitoring and studying the effects of spaceflight on private astronauts and developing health management plans for commercial space providers.
Better measurements for better health
ESA astronaut Tim Peake conducts operations for the Vascular Echo experiment. NASA Vascular Echo, an investigation from CSA (Canadian Space Agency), examined blood vessels and the heart using a variety of tools, including ultrasound. A published study suggests that 3D imaging technology might better measure cardiac and vascular anatomy than the 2D system routinely used on the space station. The research team also developed a probe for the ultrasound device that better directs the beam, making it possible for someone who is not an expert in sonography to take precise measurements. This technology could help astronauts monitor heart health and treat cardiovascular issues on a long-duration mission to the Moon or Mars. The technology also could help patients on Earth who live in remote locations, where an ultrasound operator may not always be available.
Long-term heart health in space
As part of exploring ways to keep astronauts healthy on missions to the Moon and Mars, NASA is conducting a suite of space station studies called CIPHER that looks at the effects of spaceflight lasting up to a year. One CIPHER study, Vascular Calcium, examines whether calcium lost from bone during spaceflight might deposit in the arteries, increasing vessel stiffness and contributing to increased risk of future cardiovascular disease. Astronaut volunteers provide blood and urine samples and undergo ultrasound and high-resolution scans of their bones and arteries for this investigation. Another CIPHER study, Coronary Responses, uses advanced imaging tests to measure heart and artery response to spaceflight.
These studies will help scientists determine whether spaceflight accelerates narrowing and stiffening of the arteries, known as atherosclerosis, or increases the risk of atrial fibrillation, a rapid and irregular heartbeat seen in middle-aged adults. This work also could help identify potential biomarkers and early warning indicators of cardiovascular disease.
Melissa Gaskill
International Space Station Research Communications Team
Johnson Space Center
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By European Space Agency
The European Space Agency (ESA) has endorsed the United Nations' (UN) designation of 2029 as the International Year of Asteroid Awareness and Planetary Defence.
The initiative will foster international collaboration in the field of planetary defence and educate the public on the risks and opportunities associated with near-Earth asteroids.
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By NASA
The NASA Ames Science Directorate recognizes the outstanding contributions of (pictured left to right) Michael Flynn, Ross Beyer, and Matt Johnson. Their commitment to the NASA mission represents the entrepreneurial spirit, technical expertise, and collaborative disposition needed to explore this world and beyond
Space Biosciences Star: Michael Flynn
Michael Flynn, a senior scientist and engineer in the Space Biosciences Branch, has over 35 years of groundbreaking contributions to life support systems and space technologies, including over 120 peer-reviewed publications and multiple prestigious awards. He is being recognized for his leadership in advancing water recycling technologies and his dedication to fostering innovation and mentorship within his team.
Space Science and Astrobiology Star: Ross Beyer
Ross Beyer is a planetary scientist in the Planetary Systems Branch for the Search for Extraterrestrial Intelligence (SETI) Institute, with scientific expertise in geomorphology, surface processes, and remote sensing of the solid bodies in our Solar System. He is recognized for exemplifying leadership and teamwork through his latest selected 5-year proposal to support the Ames Stereo Pipeline, implementing open science processes, and serving as a Co-Investigator on several flight missions.
Earth Science Star: Matthew Johnson
Matthew Johnson is a research scientist in the Biospheric Science Branch (code SGE). Matt is recognized for his exemplary productivity in publishing in high-impact journals and success at leading and co-developing competitive proposals, while serving as a mentor and leader. Matt recently expanded his leadership skills by assuming the position of Assistant Branch Chief of SGE and as an invited lead co-author of the December 2024 PANGEA white paper, which could lead to a new NASA HQ Terrestrial Ecology campaign.
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By NASA
For astronauts aboard the International Space Station, staying connected to loved ones and maintaining a sense of normalcy is critical. That is where Tandra Gill Spain, a computer resources senior project manager in NASA’s Avionics and Software Office, comes in. Spain leads the integration of applications on Apple devices and the hardware integration on the Joint Station Local Area Network, which connects the systems from various space agencies on the International Space Station. She also provides technical lead support to the Systems Engineering and Space Operations Computing teams and certifies hardware for use on the orbiting laboratory.
Spain shares about her career with NASA and more. Read on to learn about her story, her favorite project, and the advice she has for the next generation of explorers.
Tandra Spain’s official NASA portrait. NASA Where are you from?
I am from Milwaukee, Wisconsin.
Tell us about your role at NASA.
I am the Apple subsystem manager where I lead the integration of applications on Apple devices as well as the hardware integration on the Joint Station Local Area Network. We use a variety of different software but I work specifically with our Apple products. I also provide technical lead support to the Systems Engineering and Space Operations Computing teams. In addition, I select and oversee the certification of hardware for use on the International Space Station, and I research commonly used technology and assess applicability to space operations.
How would you describe your job to family or friends who may not be familiar with NASA?
I normalize living and working in space by providing the comforts and conveniences of living on Earth.
Tandra spain
Computer Resources Senior Project Manager
I get the opportunity to provide the iPads and associated applications that give astronauts the resources to access the internet. Having access to the internet affords them the opportunity to stay as connected as they desire with what is going on back home on Earth (e.g., stream media content, stay in touch with family and friends, and even pay bills). I also provide hardware such as Bluetooth speakers, AirPods, video projectors, and screens.
How long have you been working for NASA?
I have been with the agency for 30 years, including 22 years as a contractor.
What advice would you give to young individuals aspiring to work in the space industry or at NASA?
I have found that there is a place for just about everyone at NASA, therefore, follow your passion. Although many of us are, you don’t have to be a scientist or engineer to work at NASA. Yearn to learn. Pause and listen to those around you. You don’t know what you don’t know, and you will be amazed what gems you’ll learn in the most unexpected situations.
Additionally, be flexible and find gratitude in every experience. Many of the roles that I’ve had over the years didn’t come from a well-crafted, laid-out plan that I executed, but came from taking advantage of the opportunities that presented themselves and doing them to the best of my ability.
Tandra Spain and her husband, Ivan, with NASA astronaut and Flight Director TJ Creamer when she was awarded the Silver Snoopy Award. What was your path to NASA?
I moved to Houston to work at NASA’s Johnson Space Center immediately upon graduating from college.
Is there someone in the space, aerospace, or science industry that has motivated or inspired you to work for the space program? Or someone you discovered while working for NASA who inspires you?
I spent over half of my career in the Astronaut Office, and I’ve been influenced in different ways by different people, so it wouldn’t be fair to pick just one!
What is your favorite NASA memory?
I’ve worked on so many meaningful projects, but there are two recent projects that stand out.
Humans were not created to be alone, and connection is extremely important. I was able to provide a telehealth platform for astronauts to autonomously video conference with friends and family whenever an internet connection is available. Prior to having this capability, crew were limited to one scheduled video conference a week. It makes me emotional to think that we have moms and dads orbiting the Earth on the space station and they can see their babies before they go to bed, when they wake up in the morning, or even in the middle of the night if needed.
In addition, since iPads are used for work as well as personal activities on station, it is important for my team to be able to efficiently keep the applications and security patches up to date. We completed the software integration and are in the process of wrapping up the certification of the Mac Mini to provide this capability. This will allow us to keep up with all software updates that Apple releases on a regular basis and minimize the amount of crew and flight controller team time associated with the task by approximately 85%.
Tandra Spain, her mother, Marva Herndon, and her daughter, Sasha, at her daughter’s high school graduation in 2024. What do you love sharing about station? What’s important to get across to general audiences to help them understand the benefits to life on Earth?
When I speak to the public about the space station, I like to compare our everyday lives on Earth to life on the station and highlight the use of technology to maintain the connection to those on Earth. For example, most people have a phone. Besides making a phone call, what do you use your phone for? It is amazing to know that the same capabilities exist on station, such as using apps, participating in parent teacher conferences, and more.
If you could have dinner with any astronaut, past or present, who would it be?
I would have dinner with NASA astronaut Ron McNair. He graduated from the same university as I did, and I’ve heard great stories about him.
Do you have a favorite space-related memory or moment that stands out to you?
As I mentioned previously, human connection is extremely important. As an engineer in the Astronaut Office, I worked on a project that provided more frequent email updates when Ku-Band communication was available. Previously, email was synced two to three times a day, and less on the weekend. When the capability went active, I sent the first email exchange.
What are some of the key projects you’ve worked on during your time at NASA? What have been your favorite?
There have been so many projects over the past 30 years that I don’t think I could select just one. There is something however, that I’ve done on many occasions that has brought me pure joy, which is attending outreach events as Johnson’s “Cosmo” mascot, especially Houston Astros games.
Tandra Spain representing NASA as “Cosmo” the astronaut mascot at a Houston Astros baseball game. What are your hobbies/things you enjoy outside of work?
I enjoy crafting, traveling, mentoring students in Pearland Independent School District, spending time with family, and my Rooted Together community.
Day launch or night launch?
Night launch!
Favorite space movie?
Star Wars (the original version)
NASA “worm” or “meatball” logo?
Meatball
Every day, we’re conducting exciting research aboard our orbiting laboratory that will help us explore further into space and bring benefits back to people on Earth. You can keep up with the latest news, videos, and pictures about space station science on the Station Research & Technology news page. It’s a curated hub of space station research digital media from Johnson and other centers and space agencies.
Sign up for our weekly email newsletter to get the updates delivered directly to you.
Follow updates on social media at @ISS_Research on Twitter, and on the space station accounts on Facebook and Instagram.
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