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NASA astronaut and Expedition 72 Flight Engineer Nick Hague pedals on the Cycle Ergometer with Vibration Isolation and Stabilization (CEVIS), an exercise cycle located aboard the International Space Station’s Destiny laboratory module. CEVIS provides aerobic and cardiovascular conditioning through recumbent (leaning back position) or upright cycling activities.NASA Lee esta historia en español aquí.
The International Space Station is humanity’s home in space and a research station orbiting about 250 miles above the Earth. NASA and its international partners have maintained a continuous human presence aboard the space station for more than 24 years, conducting research that is not possible on Earth.
The people living and working aboard the microgravity laboratory also are part of the research being conducted, helping to address complex human health issues on Earth and prepare humanity for travel farther than ever before, including the Moon and Mars.
Here are a few frequently asked questions about how NASA and its team of medical physicians, psychologists, nutritionists, exercise scientists, and other specialized caretakers ensure astronauts’ health and fitness aboard the orbiting laboratory.
How long is a typical stay aboard the International Space Station?
A typical mission to the International Space Station lasts about six months, but can vary based on visiting spacecraft schedules, mission priorities, and other factors. NASA astronauts also have remained aboard the space station for longer periods of time. These are known as long-duration missions, and previous missions have given NASA volumes of data about long-term spaceflight and its effects on the human body, which the agency applies to any crewed mission.
During long-duration missions, NASA’s team of medical professionals focus on optimizing astronauts’ physical and behavioral health and their performance to help ensure mission success. These efforts also are helping NASA prepare for future human missions to the Moon, Mars, and beyond.
How does NASA keep astronauts healthy while in space?
NASA has a team of medical doctors, psychologists, and others on the ground dedicated to supporting the health and well-being of astronauts before, during, and after each space mission. NASA assigns physicians with specialized training in space medicine, called flight surgeons, to each crew once named to a mission. Flight surgeons oversee the health care and medical training as crew members prepare for their mission, and they monitor the crew’s health before, during, and after their mission to the space station.
How does NASA support its astronauts’ mental and emotional well-being while in space?
The NASA behavioral health team provides individually determined psychological support services for crew members and their families during each mission. Ensuring astronauts can thrive in extreme environments starts as early as the astronaut selection process, in which applicants are evaluated on competencies such as adaptability and resilience. Astronauts receive extensive training to help them use self-assessment tools and treatments to manage their behavioral health. NASA also provides training in expeditionary skills to prepare every astronaut for missions on important competencies, such as self-care and team care, communication, and leadership and followership skills.
To help maintain motivation and morale aboard the space station, astronauts can email, call, and video conference with their family and friends, receive crew care packages aboard NASA’s cargo resupply missions, and teleconference with a psychologist, if needed.
How does microgravity affect astronaut physical health?
In microgravity, without the continuous load of Earth’s gravity, there are many changes to the human body. NASA understands many of the human system responses to the space environment, including adaptations to bone density, muscle, sensory-motor, and cardiovascular health, but there is still much to learn. These spaceflight effects vary from astronaut to astronaut, so NASA flight surgeons regularly monitor each crew member’s health during a mission and individualize diet and fitness routines to prioritize health and fitness while in space.
Why do astronauts exercise in space?
Each astronaut aboard the orbiting laboratory engages in specifically designed, Earth-like exercise plans. To maintain their strength and endurance, crew members are scheduled for two and a half hours of daily exercise to support muscle, bone, aerobic, and sensorimotor health. Current equipment onboard the space station includes the ARED (Advanced Resistive Exercise Device), which mimics weightlifting; a treadmill, called T2; and the CEVIS (Cycle Ergometer with Vibration Isolation and Stabilization System) for cardiovascular exercise.
What roles do food and nutrition play in supporting astronaut health?
Nutrition plays a critical role in maintaining an astronaut’s health and optimal performance before, during, and after their mission. Food also plays a psychosocial role during an astronaut’s long-duration stay aboard the space station. Experts working in NASA’s Space Food Systems Laboratory at the agency’s Johnson Space Center in Houston develop foods that are nutritious and appetizing. Crew members also have the opportunity to supplement the menu with personal favorites and off-the-shelf items, which can provide a taste of home.
NASA astronaut and Expedition 71 Flight Engineer Tracy C. Dyson is pictured in the galley aboard the International Space Station’s Unity module showing off food packets from JAXA (Japan Aerospace Exploration Agency).NASA How does NASA know whether astronauts are getting the proper nutrients?
NASA’s nutritional biochemistry dietitians and scientists determine the nutrients (vitamins, minerals, calories) the astronauts require while in space. This team tracks what each crew member eats through a tablet-based tracking program, which each astronaut completes daily. The data from the app is sent to the dietitians weekly to monitor dietary intake. Analyzing astronaut blood and urine samples taken before, during, and after space missions is a crucial part of studying how their bodies respond to the unique conditions of spaceflight. These samples provide valuable insight into how each astronaut adapts to microgravity, radiation, and other factors that affect human physiology in space.
How do astronauts train to work together while in space?
In addition to technical training, astronauts participate in team skills training. They learn effective group living skills and how to look out for and support one another. Due to its remote and isolated nature, long-duration spaceflight can make teamwork difficult. Astronauts must maintain situational awareness and implement the flight program in an ever-changing environment. Therefore, effective communication is critical when working as a team aboard station and with multiple support teams on the ground. Astronauts also need to be able to communicate complex information to people with different professional backgrounds. Ultimately, astronauts are people living and working together aboard the station and must be able to do a highly technical job and resolve any interpersonal issues that might arise.
What happens if there is a medical emergency on the space station?
All astronauts undergo medical training and have regular contact with a team of doctors closely monitoring their health on the ground. NASA also maintains a robust pharmacy and a suite of medical equipment onboard the space station to treat various conditions and injuries. If a medical emergency requires a return to Earth, the crew will return in the spacecraft they launched aboard to receive urgent medical care on the ground.
Expedition 69 NASA astronaut Frank Rubio is seen resting and talking with NASA ISS Program Manager Joel Montalbano, kneeling left, NASA Flight Surgeon Josef Schmid, red hat, and NASA Chief of the Astronaut Office Joe Acaba, outside the Soyuz MS-23 spacecraft after he landed with Roscosmos cosmonauts Sergey Prokopyev and Dmitri Petelin in a remote area near the town of Zhezkazgan, Kazakhstan on Wednesday, Sept. 27, 2023.NASA/Bill Ingalls Learn more about NASA’s Human Health and Performance Directorate at:
www.nasa.gov/hhp
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By NASA
4 min read
Preparations for Next Moonwalk Simulations Underway (and Underwater)
The mystery of why life uses molecules with specific orientations has deepened with a NASA-funded discovery that RNA — a key molecule thought to have potentially held the instructions for life before DNA emerged — can favor making the building blocks of proteins in either the left-hand or the right-hand orientation. Resolving this mystery could provide clues to the origin of life. The findings appear in research recently published in Nature Communications.
Proteins are the workhorse molecules of life, used in everything from structures like hair to enzymes (catalysts that speed up or regulate chemical reactions). Just as the 26 letters of the alphabet are arranged in limitless combinations to make words, life uses 20 different amino acid building blocks in a huge variety of arrangements to make millions of different proteins. Some amino acid molecules can be built in two ways, such that mirror-image versions exist, like your hands, and life uses the left-handed variety of these amino acids. Although life based on right-handed amino acids would presumably work fine, the two mirror images are rarely mixed in biology, a characteristic of life called homochirality. It is a mystery to scientists why life chose the left-handed variety over the right-handed one.
A diagram of left-handed and right-handed versions of the amino acid isovaline, found in the Murchison meteorite.NASA DNA (deoxyribonucleic acid) is the molecule that holds the instructions for building and running a living organism. However, DNA is complex and specialized; it “subcontracts” the work of reading the instructions to RNA (ribonucleic acid) molecules and building proteins to ribosome molecules. DNA’s specialization and complexity lead scientists to think that something simpler should have preceded it billions of years ago during the early evolution of life. A leading candidate for this is RNA, which can both store genetic information and build proteins. The hypothesis that RNA may have preceded DNA is called the “RNA world” hypothesis.
If the RNA world proposition is correct, then perhaps something about RNA caused it to favor building left-handed proteins over right-handed ones. However, the new work did not support this idea, deepening the mystery of why life went with left-handed proteins.
The experiment tested RNA molecules that act like enzymes to build proteins, called ribozymes. “The experiment demonstrated that ribozymes can favor either left- or right-handed amino acids, indicating that RNA worlds, in general, would not necessarily have a strong bias for the form of amino acids we observe in biology now,” said Irene Chen, of the University of California, Los Angeles (UCLA) Samueli School of Engineering, corresponding author of the Nature Communications paper.
In the experiment, the researchers simulated what could have been early-Earth conditions of the RNA world. They incubated a solution containing ribozymes and amino acid precursors to see the relative percentages of the right-handed and left-handed amino acid, phenylalanine, that it would help produce. They tested 15 different ribozyme combinations and found that ribozymes can favor either left-handed or right-handed amino acids. This suggested that RNA did not initially have a predisposed chemical bias for one form of amino acids. This lack of preference challenges the notion that early life was predisposed to select left-handed-amino acids, which dominate in modern proteins.
“The findings suggest that life’s eventual homochirality might not be a result of chemical determinism but could have emerged through later evolutionary pressures,” said co-author Alberto Vázquez-Salazar, a UCLA postdoctoral scholar and member of Chen’s research group.
Earth’s prebiotic history lies beyond the oldest part of the fossil record, which has been erased by plate tectonics, the slow churning of Earth’s crust. During that time, the planet was likely bombarded by asteroids, which may have delivered some of life’s building blocks, such as amino acids. In parallel to chemical experiments, other origin-of-life researchers have been looking at molecular evidence from meteorites and asteroids.
“Understanding the chemical properties of life helps us know what to look for in our search for life across the solar system,” said co-author Jason Dworkin, senior scientist for astrobiology at NASA’s Goddard Space Flight Center in Greenbelt, Maryland, and director of Goddard’s Astrobiology Analytical Laboratory.
Dworkin is the project scientist on NASA’s OSIRIS-REx mission, which extracted samples from the asteroid Bennu and delivered them to Earth last year for further study.
“We are analyzing OSIRIS-REx samples for the chirality (handedness) of individual amino acids, and in the future, samples from Mars will also be tested in laboratories for evidence of life including ribozymes and proteins,” said Dworkin.
The research was supported by grants from NASA, the Simons Foundation Collaboration on the Origin of Life, and the National Science Foundation. Vázquez-Salazar acknowledges support through the NASA Postdoctoral Program, which is administered by Oak Ridge Associated Universities under contract with NASA.
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Last Updated Nov 21, 2024 EditorWilliam SteigerwaldContactNancy N. Jonesnancy.n.jones@nasa.govLocationGoddard Space Flight Center Related Terms
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In-space manufacturing and assembly are vital to NASA’s long-term exploration goals, especially for the Moon and Mars missions. Deploying welding technology in space enables the assembly and repair of structures, reducing logistical burdens and supply needs from Earth. The unique challenges and extreme conditions of space–high thermal variations, microgravity, and vacuum–require advanced welding techniques and computational tools to ensure reliability, repeatability, safety, and structural integrity in one-shot weld scenarios. For the first time, this project investigates these challenges by focusing on three key factors: (1) Very low temperatures in space degrade the weldability of high thermal conductivity materials, like aluminum alloys, making it harder to achieve strong, defect-free welds. (2) The extreme vacuum in space lowers the boiling points of alloying elements, altering the keyhole geometry during welding. This selective vaporization changes the weld’s final chemical composition, affecting its microstructure and properties. (3) Microgravity nearly eliminates buoyancy-driven flow of liquid metal inside the molten pool, preventing gas bubbles from escaping, which leads to porosity and defects in the welds. By examining these critical factors using multi-scale multi-physics models integrated with physics-informed machine learning, and forward/inverse uncertainty quantification techniques, this project provides the first-ever real-time digital twin platform to evaluate welding processes under extreme space/lunar conditions. The models are validated through Earth-based experiments, parabolic flight tests, and publicly available data from different databases and agencies worldwide. Moreover, the established models will facilitate extendibility to support in-situ resource utilization on the Moon, including construction and repair using locally sourced materials like regolith. The established fundamental scientific knowledge will minimize trial-and-error, enable high-quality one-shot welds in space, and reduce the need for reworks, significantly reducing the costs and time needed for space missions.
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Pictured (clockwise) from bottom left are astronauts Charles O. Hobaugh, commander; Mike Foreman, Leland Melvin, Robert L. Satcher Jr. and Randy Bresnik, all mission specialists; along with Barry E. “Butch” Wilmore, pilot; and Nicole Stott, mission specialist.NASA The STS-129 crew members pose for a portrait following a joint news conference with the Expedition 21 crew members on Nov. 24, 2009. Astronauts Charles O. Hobaugh, Mike Foreman, Leland Melvin, Robert L. Satcher Jr., Randy Bresnik, Butch Wilmore, and Nicole Stott launched from NASA’s Kennedy Space Center in Florida on Nov. 16, 2009, aboard the space shuttle Atlantis. Traveling with them was nearly 30,000 pounds of replacement parts and equipment that would keep the orbital outpost supplied for several years to come.
The Atlantis crew performed three demanding but successful spacewalks – and enjoyed a surprise Thanksgiving dinner on the station, courtesy of the Expedition 21 crew.
Image credit: NASA
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